Haplogroup B2 and subgroups are found among Native Americans and First Nations people in North, Central and South America.
However, occurrances of B2c, without a subgroup, are quite rare. In fact, outside of academic publications, I have only been able to find 4 individuals who are designed as haplogroup B2c that have been full sequence tested. There are a few other candidates (at least two of which hail from the Chaco Canyon region,) but to confirm this haplogroup, one must test at the full sequence level at Family Tree DNA, the only testing company that tests the full mitochondria.
The second interesting part of this equation is that nearly all of haplogroup B2c with subgroups is found in the Southwest US or Mexico. However, three of the four instances of B2c (without subgroups) are NOT found in that region, but in the eastern US and Canada, as shown on the map above, where B2c (including subgroups) has never been previously found.
Individuals who will be designated as B2c at the full sequence level will be estimated as haplogroup B4’5 at the HVR1 or HVR1+HVR2 levels. The mutations that indicate B2c and other haplogroups downstream of B4’5 are found in the coding region, which is only tested by the full sequence test.
If you have only tested to the HVR1 or HVR2 level, and you match anyone with haplogroup B2c, please consider upgrading to the full sequence test. Your results could be both quite unique and very important to understanding the migration and settlement pattern of Native American ancestors.
I’ll be adding these findings to the haplogroup B2c group in the article, Native American Mitochondrial Haplogroups.
You can view more about haplogroup B2 at the Haplogroup B2 Project page here.