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MyHeritage Whole Genome Sequencing (WGS) Results and Comparison

Roberta Estes

I’m excited to receive my low-pass whole-genome sequencing test results from MyHeritage. When MyHeritage initially introduced their new test, I wrote about what that means in the article, MyHeritage Introduces a Low-Pass Whole Genome Autosomal DNA Test and Why It Matters.

In that article, I said I was ordering a WGS test and would publish a comparison of the new test with the two tests I’ve previously taken with MyHeritage, plus a test I uploaded to MyHeritage from FamilyTreeDNA in 2016.

Before I review these comparative results with you, I want to properly set expectations.

What To Expect from the MyHeritage Whole Genome Sequence (WGS) Test

From Ran Snir, Vice President of Product Management for MyHeritage DNA:

  1. Those who take a MyHeritage DNA test now are all sequenced with WGS and will receive the same access to features and results as those who have taken a MyHeritage DNA test and were genotyped with an old chip in the past. In fact, all samples processed by the lab in December were already processed with WGS.
  2. The transition to WGS does not introduce new features and capabilities immediately.
  3. The new WGS technology has minor implications when it comes to the ethnicity estimate results and DNA Matches, but people should not expect to get “something completely different”.
  4. The transition to WGS and having more people processed with it opens the door for deeper research and more insights. It will allow MyHeritage to drastically improve its phasing, imputation and matching algorithms. This will take time as MyHeritage needs to amass a lot of data first. In the long run, MyHeritage plans to improve the product, build new features and introduce new capabilities which will be based on learnings from WGS.

Thank you, Ran.

In this article, I am not focusing on ethnicity, but on DNA matches, which I depend on to help me unravel those pesky genealogy puzzles.

Also, please note, some features I’m discussing here are free with the purchase of a DNA test, and others require a subscription at some level. I have a subscription, and I use it nearly every day.

Coupon Code for a $20 DNA Test

That said, if you already know you want to order the WGS test, or you’re a new tester, use this special coupon code at checkout to reduce the test to $20 through the end of February 2026. That’s a great value!

Coupon Code: RobertaFeb26

Now, let’s look at my results when comparing the WGS test to the results of my other three tests at MyHeritage.

How does the new WGS test fare?

My Results

Before ordering my WGS test from MyHeritage, I already had three tests at MyHeritage to choose from.

MyHeritage allows you to select between different tests, including uploads and tests you’ve taken at MyHeritage at different times. There’s absolutely no need to delete older tests there, and in fact, I recommend that you don’t. This article illustrates why.

My four tests include:

FTDNA 2016 MH Health 2019 MH 2024 MH WGS
Total Matches 19,722 17,179 17,767 17,676
TOFR 128 111 108 Not ready

This chart shows the total number of matches and Theories of Family Relativity for each test in January 2026.

What Are Theories of Family Relativity (TOFR)?

I have several very useful Theories of Family Relativity (TOFR) where MyHeritage uses trees and other documentation, such as census records, to connect you and your DNA matches to common ancestors. TOFR is one of MyHeritage’s most beneficial tools.

In this example, my match only provided their father’s name, but that name was linked to our common ancestors by connecting through a FamilySearch tree. Often, multiple potential relationships and paths are shown. Like with any other tool, each theory needs to be reviewed for accuracy.

Please note that TOFR is only run periodically and has not yet been calculated for the WGS test results. I’m sure that will happen soon.

Evaluating Matches

I wanted to know if (and how) the same people matched me on the different tests, including the new low-pass whole genome (WGS).

To compare the results of all four tests, I created a side-by-side comparison spreadsheet.

The Spreadsheet

I created a spreadsheet where I recorded 434 individual matches by entering information in the following columns:

I included several other columns in my spreadsheet for my own genealogical research purposes that show my matches’ tree size, and the actual lineage from them to our common ancestor couple. However, for comparing matches and accuracy, I’ve utilized the columns indicated above.

Match Sources

I wanted to compare different types of matches, meaning not just the closest or the most distant, or only the matches I can identify. These are the sources of the matches I compared.

However, after I finished transcribing each of those 100 matches into the spreadsheet and started transcribing the top 100 matches for the MyHeritage 2019 test, I quickly realized that the top 100 matches were not the same between tests. Therefore, I used the top 100 matches from all 4 tests. For every name included from any test in the top 100, I included the matching cM amount from all four tests. This means that in total, there are more than 100 in the “Top 100”, so now it’s called the Top 100/150, but all of the top 100 matches from each of the four tests are included in the spreadsheet. In total, there are about 220 in that category.

When I finished listing all of these matches, I had 434 to work with for this comparison. .

Minimum Matching

The minimum MyHeritage reported match is 8 cM, and at that level, a surprising number of tests don’t match either parent, although some clearly match with close relatives on that parent’s side, which means that either:

About Imputation

Imputation is a widely used technology among vendors to bridge small sections of unread DNA. This is useful when comparing files from different vendors for matching.

Vendors use imputation internally too.

For example, vendors often use different DNA chips in the lab. They sometimes change chips internally, as well, for a variety of reasons. Regardless of why, the same locations aren’t always read, or aren’t read successfully. Imputation levels the playing field, allowing backwards compatibility, and compatibility for matching across platforms. Imputation fills in the blanks to equalize those files, allowing them to be compared for matching.

Let me give you an example. Let’s say you have the letters c_t, where the middle letter between c and t is missing. In English, there are a limited number of letters that can be. To begin with, it must be a vowel. In this case, it has to be either a, o or u. Next, looking at context, if the surrounding words are “the c_t chased a mouse,” the missing word is not cut or cot. It’s almost certainly cat, so the “a” is filled in using imputation.

Imputation usually works well, but occasionally it can extend matching areas improperly. This has always been true, and it’s still true with the new low-pass WGS test. The new WGS test only scans the genome twice to keep the test affordable. Any “no read” area must be imputed. I wrote about imputation here.

Ok, back to the MyHeritage comparison!

Test Comparison Methodology

If you’re recreating this process with your own results:

Select the test you want to search for matches, and record the people you want to cross-check. I began the process with my FTDNA test that I uploaded to MyHeritage in 2016.

I entered the matches on my spreadsheet, recording the matching cM amount. Then I selected the other tests, one by one, and searched for the same match name.

In this case, I started with the FTDNA 2016 test. Jane Jones (not her real name) matched me at 744 cM.

Then I selected the MyHeritage 2019 test, searched for Jane’s name, and recorded the match amount – 739 cM. I did the same with the 2024 test, and last, the WGS test.

When searching by surname at MyHeritage, don’t always expect the person to be at the top of the list where you might expect. Be sure to scroll down a bit, even to page two, especially with common names. MyHeritage also displays people with the same surname in their trees.

Match Analysis

As we work through these match results, keep in mind that the comparison percentage numbers only pertain to the 434 people that I’ve selected to compare across all four tests. This is NOT the total amount in any category for all of my matches. There’s no way to make that determination without manually comparing every single match for all four tests – which is why I selected what I felt was a representative sample.

You’ll quickly discover that many people DON’T MATCH you on all the DNA tests. You’ll notice as I give examples that I’ve colored coded some cells for my own use in both interpreting matches as well as sorting them. For example, People who don’t match on that test were labeled “none” and colored bright blue. Eventually, I simply entered “0” instead of the word “none” so I could perform math functions on those cells. I retained the blue so I could filter by cell color. You get the idea.

Using the new WGS test, 16 people (3.7% of 434) match me ONLY on the WGS test, but do NOT match me on any of the other tests.

Interestingly enough, they are all in the Top 100/150 category for the WGS test. Those match results range from 45 cMs to 53 cMs.

That’s NOT a trivial amount of DNA. It’s rather confusing how someone could match at that level on the WGS test, but not at all on the others.

Equally as interesting is that two of those 16 WGS matches don’t match either of my parents.

So, let’s say this another way to be clear – I only see these matches on the WGS test, and none of the other tests.

How Many People Match Me on Only One Test?

Ok, so how many people match me on ONLY one test?

FTDNA 2016 Only Matches MH 2019 Only Matches MH 2024 Only Matches MH WGS Only Matches
44 (10.1%) 3 (0.7%) 3 (0.7%) 16 (3.7%)

Extrapolating these percentages to the rest of my matches suggests the following number of people would match ONLY on this test in the entire match list for each test.

FTDNA 2016 MH Health 2019 MH 2024 MH WGS
Total Matches 19,722 17,179 17,767 17,676
Extrapolated Matches on Only This Test 10.1% or 1992 matches 0.7% or 120 matches 0.7% or 124 matches 3.7% or 654 matches

 How Many People DON’T Match Me on a Specific Test?

Now, how many people DON’T match me on a specific test?

No FTDNA Match No MH 2019 Match No MH 2024 Match No MH WGS Match
36 (8.3%) 117 (27%) 126 (30%) 96 (22%)

Extrapolating these percentages provides an extrapolated number of matches that I don’t match on any specific test, but that I do match on at least one other test.

FTDNA 2016 MH Health 2019 MH 2024 MH WGS
Total Matches 19,722 17,179 17,767 17,676
Extrapolated # That Don’t Match on This Test 8.3% or 1637 matches 27% or 4638 matches 39% or 5330 matches 22% or 3,889 matches

How Many Match Me On All Tests

The Largest Differences Between Tests

Another question might be how large the difference is between the various matches.

I calculated the largest differences between the highest and lowest match values between the four tests, and placed that value in column G. This means that I subtracted the lowest value of the four tests on this particular match, from the highest value.

In the first row, that means I subtracted 0, the MH 2019 test value, from 75, the WGS test value. The difference between the lowest and highest values is 75 cMs.

Next, I sorted, highest to lowest in column G, so the largest difference is displayed at the top.

I was VERY surprised to see a difference as high as 75 cM, so let’s evaluate the results where the difference is 50 cM or greater. Thirteen matches fall into this category.

Difference Range

Next, let’s review the entire range of differences, meaning the largest matching difference for any one person across all four tests, by group. I’m including all 434 here so you can judge for yourself.

The 8 cM difference has the most of any value or category because this is the lowest level of matching at MyHeritage. Many tests have a minimum level match on a test or tests, and no others.

The match differences at 5 cM and below are inconsequential. 57 matches fall into this category.

Commentary

One of the indicators of a valid match is if a parent has tested and also matches,

Of these 434 matches, 35 match neither parent, and most of those are at the smallest match level, meaning 8 cM. Of all the match amounts, that would be the least reliable, and most likely to be a false positive match, or identical by chance.

However, that’s not universally the case. Some WGS results match people at significantly higher levels, but don’t match parents. Two WGS matches match people at 47 and 49 cMs, respectively, and not on any of the other tests. Those two WGS matches don’t match either parent.

After reviewing all 434 selected matches, it appears that both the FamilyTreeDNA 2016 test, and the WGS test produce the most consistent and reliable results of the four tests.

44 people, or 10%, match on BOTH the WGS and the FTDNA tests, but neither of the other two tests. A total of 13.8% match EITHER the FTDNA test OR the WGS test, but not the others.

Conclusions

I think we can draw several conclusions from this comparison.

First, let’s evaluate the number of matches. Looking at the differences between the total number of matches between the various tests, especially the three MyHeritage tests, over time, isn’t that great. That’s exactly why you can’t depend on these numbers as an accurate comparison.

FTDNA 2016 MH Health 2019 MH 2024 MH WGS
Total Matches 19,722 17,179 17,767 17,676

There are only a few hundred differences between the three MyHeritage tests, and about 2000 between the FamilyTreeDNA test uploaded in 2016 and the various MyHeritage tests. That’s a substantial difference.

The difference number of matches between tests may seem irrelevant, especially the MyHeritage tests, until you realize that those who match AREN’T ALL THE SAME PEOPLE. In other words, comparing the MyHeritage 2024 test with the WGS test only shows a difference of 91 matches. This DOES NOT mean that the MyHeritage 2024 test and the WGS test have 17,676 of the same people who match both tests, and that the 2024 test simply has 91 more matches than the WGS test.

As we’ve seen, many people who appear on any one match list don’t appear on other match lists.

Our analysis showed that 44.9% of my 434 matches compared appear on all match lists, which means that more than half of my matches appear on one or more match lists, and not the others. Therefore, just comparing the number of matches isn’t really relevant. You need to compare the people included on all the different tests, which is why I created my spreadsheet and included people from a wide variety of sources.

3.7% of my matches on the WGS test were not on any other test, which extrapolates to approximately 654 of my total WGS matches that I wouldn’t receive any other way.

I care a great deal about those matches, especially since at least some appear to be high value.

Yes, I absolutely, positively want those matches, especially when you consider that some of the matching differences are as high as 75 cM. A 75 cM match can be in the second, third or fourth cousin range.

Realistically, they may or may not be valid or useful matches – but if I don’t have the opportunity to compare them, I’ll never know.

Should You Purchase the WGS Test If You’ve Already Tested?

So, now for the question you’re surely asking yourself.

Truthfully, when I ordered my test back in December, I was ambivalent. I only ordered it to do this comparison for my blog readers – and I really dislike spending money on something that I don’t think will benefit me.

Note the words “don’t think.”

I’ve changed my mind, for several reasons, and I’m glad I ordered the test.

The thing that changed my mind was that I received a nontrivial amount of matches on the WGS test that I didn’t receive on any of the others – even if some of them turn out to be identical by chance.

Since we can’t go back in time and take the earlier tests, and MyHeritage no longer accepts uploads from other vendors, our decision now is whether or not we should take the new WGS test, or not, especially if we already have a DNA test at MyHeritage.

If you’re a new tester, by all means, test at all four of the main vendors. DNA matching is the best thing since sliced bread.

However, the people I’m really speaking to here are those who already have a test of some sort at MyHeritage.

Here’s the bottom line:

My Biggest Regret

As Ran Snir said, new features and developments at MyHeritage will be based on the WGS test. We don’t know what those developments might be, or when they will become available. But it’s very clear that while testers on the older testing platforms will receive as much as MyHeritage can give them, the MyHeritage DNA future is being build on the WGS platform. I want to be there and benefit from new discoveries.

My biggest regret is that my parents aren’t around to take the new WGS test – and neither are several other family members.

Of the 15 family members whose tests I manage at MyHeritage, 9 are deceased, and I think that four more are as well. Two others are now quite elderly and are no longer able to consent or retest.

Your closest family members are your DNA anchors, identifying lineages and pointing you in specific directions, guiding your research.

The very best thing you can do for your genetic genealogy is to test your grandparents if they are living, and your parents. If they aren’t available, test your closest relatives such as grandparents, siblings, aunts, uncles and first cousins.

Preparing for the Future

So, here’s my advice:

Why is testing your relatives important?

Close relatives will carry some of the DNA from your mutual ancestors that you don’t.

Having the known DNA of your ancestors means that you can evaluate and analyze the trees of the entire group of people who match those identified DNA segments to see if you can break down an upstream brick wall.

I’ve been successful doing this for some time – and am in the process again by combining DNA matches and traditional records research.

Coupon Code for $20 DNA Test

MyHeritage has been kind enough to provide a limited-time coupon code (RobertaFeb26) for my readers which DROPS YOUR PRICE for the DNA test to $20 through February 28th at midnight.

This is the absolute lowest price I’ve ever seen for a DNA test.

You’ll receive the following features that are included with every test:

In addition, with this code you’ll receive both Shared DNA Matches and Shared Ancestral Places that usually require a subscription.

Normally, a subscription is required to access:

If you’re interested in trying a subscription, click here to purchase a MyHeritage subscription with a free trial.

Here’s the link to purchase the DNA test, and here’s the coupon code to enter at checkout: RobertaFeb26

And yes, absolutely feel free to share the coupon code with your family, friends, and anyone else who might benefit.

Let me know how your results compare when you receive them.

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