Genetic Affairs Instructions and Resources

I’ve created this summary article that includes links to the various step-by-step instructional articles I’ve published about Genetic Affairs, a wonderful DNA analysis tool. I’ll add more articles as they are published.

Genetic Affairs is a third-party tool created by Evert-Jan Blom that works through the Genetic Affairs website for FamilyTreeDNA and 23andMe and is integrated into products for other vendors such as MyHeritage and GEDmatch. Unfortunately, one vendor, Ancestry, has issued a cease-and-desist order, preventing the usage of Genetic Affairs and other third-party tools altogether for customers who have tested there.

Different features are available at different vendors based on their product offerings, as noted below.

AutoCluster

Article: AutoClustering by Genetic Affairs

This article explains the basics of AutoClustering of matches and how autoclusters benefit genealogy.

AutoTree and AutoPedigree

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Article: Genetic Affairs Reconstructs Trees from Genetic Clusters – Even Without Your Tree or Common Ancestors

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This wonderful tool scans your matches and their trees, and constructs trees of you and your matches that share common ancestors. The best thing about this tool is that it reconstructs trees of your matches to each other in a cluster, even if you DON’T share a common ancestor in a tree with your matches (that also match each other.) This tool is HUGELY helpful in identifying ancestors that are unknown to you and includes the option for Y and mtDNA to be incorporated into the trees if you’ve taken those tests at Family Tree DNA.

AutoPedigree + WATO

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Article: Genetic Affairs: AutoPedigree Combined AutoTree with WATO to Identify Your Potential Tree Locations

WATO, short for “what are the odds,” is a calculation method that provides ranked hypothesis that show you where you “might” fit in the composite tree of your matches. This is the “AutoPedigree generate hypothesis automatically” option under AutoCluster analysis and is particularly useful for people with unknown parentage, unknown close relatives, or clusters that they can’t identify.

  • AutoPedigree+WATO can only be used with results at FamilyTreeDNA, and not at any of the other vendors for the same reasons as AutoTree/AutoPedigree. I encourage my matches to upload their DNA files from other vendors for free to FamilyTreeDNA so that everyone has more information points to work with.

AutoClusters at MyHeritage

Article: Utilizing MyHeritage AutoClusters to Analyze your DNA Matches

  • MyHeritage incorporates AutoClusters into their advanced DNA toolset for customers. Utilizing AutoClusters with DNA tools like Theories of Family Relativity and Triangulation provide a powerful 1-2-3 punch to identify family groupings.
  • Additionally, MyHeritage provides trees, Smart Matches, Shared Ancestral Surnames, Shared Ancestral Places, Shared DNA Matches and the ability to download both your shared match information along with shared segment data.
  • This article provides step-by-step information about how to use each tool and is paired with a free webinar.

AutoKinship 

Article: Genetic Affairs – New AutoKinship Tool Predicts Relationships and Builds Genetic Trees

  • The AutoKinship tool constructs multiple genetic trees for each cluster based on your clustered matches at 23andMe, and their relationships to you and each other.
  • An AutoCluster is included with AutoKinship along with membership and segment information for each cluster, including triangulation for cluster members.
  • A relationship matrix shows how closely your matches are related to each other.
  • AutoKinship paints your matches on your chromosomes and provides overlapping segment information
  • The Surname Enrichment option provides common surnames in each cluster and shows you which members list each surname at 23andMe. 
  • A stand-alone manual version of AutoKinship is available at Genetic Affairs for MyHeritage profiles, with a tutorial, here.

AutoSegment at GEDmatch

AutoSegment is available at GEDmatch under the Tier 1 tools.

AutoSegment at GEDmatch clusters your TRIANGULATED matches together in cluster groups and paints those segments on your chromosomes by cluster.

Article: AutoSegment Triangulation Cluster Tool at GEDmatch

  • AutoSegment can perform this function at GEDmatch because Genetic Affairs can determine not only that your matches match you, but that they also match each other, and on which segment(s).
  • AutoSegment colored cluster cells indicate triangulation, not just matching.
  • AutoSegment offers several options, including the option to remove segments in known pileup areas.
  • AutoSegment provides a Pileup Report, whether you choose to remove segments in pileup regions or not.
  • In addition to the normal HTML cluster file, AutoSegment also offers an Excel option.
  • The Excel file also groups your clustered matches by chromosome.
  • AutoSegment provides the option of viewing where each person matches you, including segments that triangulate and those that do not triangulate with others.
  • AutoSegment provides an option to upload the results to DNAPainter.
  • AutoSegment provides information on linked clusters where individuals are members of more than one cluster.
  • AutoCluster provides cluster analysis in various formats, complete with links to trees.

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9 thoughts on “Genetic Affairs Instructions and Resources

  1. Pingback: Genetic Affairs Instructions and Resources — DNAeXplained – Genetic Genealogy | Ups and Downs of Family History V2.0

  2. Thanks for summarizing the offering from Genetic Affairs wrt the various DNA companies. This gets confusing.

    I just tried the Autocluster and auto tree feature on my FTDNA data. I got back an amazing amount of information. I liked the Cluster group data By chromosome, very useful.

    There also seemed to be a lot of shared location data by group. It will take me a while to look through all of this. I seemed to get less information on trees, maybe that is because my groups are small.

  3. Pingback: Utilizing MyHeritage AutoClusters to Analyze your DNA Matches | DNAeXplained – Genetic Genealogy

  4. Pingback: Triangulation Resources In One Place | DNAeXplained – Genetic Genealogy

  5. You are emphasizing that the AutoSegment report on GedMatch provide triangulated segments (while the AutoCluster report does not).
    Do the AutoSegment report on Genetic Affairs also provide triangulated segments? Are they the same in this matter?

    • Hi Heidi, excellent question. There are different scenarios possible that are linked to this question. If you run AutoSegment using locally downloaded files from 23andme, MyHeritage or FTDNA the AutoSegment tool can only identify overlapping segments.
      The exception is GEDmatch, since a triangulation file is also provided which then is used to verify overlapping segments.

      If you run AutoSegment ICW for FTDNA, we first download the segments, perform the clustering on overlapping segments and retrieve shared matches for matches that are linked to segment clusters. Next, we redo the segment clustering identification and use shared match data to assist in the overlapping segment identification.
      Overlapping segments linked to DNA matches that are not a shared match of each other are removed, thereby improving the chance of getting triangulated segments. The same is done for 23andme by using the DNA overlap feature, although that needs to be fixed in the upcoming weeks (23andme changed the underlying format).

      Hope this answered your question, if not, feel free to contact us (https://members.geneticaffairs.com/contactus).

  6. Pingback: AutoKinship at GEDmatch by Genetic Affairs | DNAeXplained – Genetic Genealogy

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