Autosomal Matchmaking Vendor Comparison

Matchmaker, matchmaker…make me a match.

Indeed, matching is what autosomal DNA for genetic genealogy is all about.  Let’s take a look at the difference between matching at the various vendors and how it affects us as genetic genealogists.

Harold is my third cousin.  We have been genealogy research partners now for about 20 years on our family lines.  Fortunately, both Harold and I have encouraged our cousins and family members to test their DNA – at all 3 testing companies.  We’ve uploaded the results to GedMatch and we’ve matched, compared and triangulated until we’re blue in the face.

Hey, it keeps us off the streets:)

What this does, however, is gives us a very firm foundation to compare results at the different companies and with different tools.

Today, I’m going to take a look at how the matches differ at the different companies and at GedMatch when comparing the same people – and how it affects us as genealogists.

First, the matching thresholds aren’t the same, but we can compensate for that and we can see how the threshold differences affect our actual matches.

The following table shows the vendor autosomal matching thresholds.

Vendor Autosomal Matching Thresholds

23andMe

At 23and Me, Harold and I share a total of 133.8 cM of DNA and 21,031 SNPs spread across 6 different segments on 5 chromosomes.

Harold Me 23andMe

Family Tree DNA

At Family Tree DNA, Harold and I share 152.44 cM of DNA with 35,774 shared SNPs.

FTDNA Harold Me

Family Tree DNA reports much smaller matching segments than 23andMe and by process of inference, Ancestry.  The chart below shows Harold matching to me at Family Tree DNA.  The green overlay highlights the segments that 23andMe shows for Harold and I as matches.  The non-highlighted rows are shown at Family Tree DNA, but not at 23andMe.

Harold Me FTDNA 23andMe

Family Tree DNA does us the HUGE favor of providing all the actual matching DNA segments over 500 SNPs in length as long as we match first on a larger segment.  The other vendors remove these.

Ancestry

Utilizing a new private tool currently in beta test, Harold and I share 113.92 cM of DNA at Ancestry.  Of course, there is no segment data, so all we have is a total, which is certainly more than we had before.

Ancestry runs their customer’s DNA through a phasing process that eliminates many segments before they do matching.  Therefore, the significantly smaller cM total on Ancestry is a result of their phasing and matching routines.

However, by comparing the Ancestry total to the 23andMe total, which is the next most restrictive result, we can see the difference.

23andMe’s total is 133.8, so the difference between the 23andMe and the Ancestry match is 19.88 cM.  If you look at the 23andMe matches, you’ll notice that the two smallest segment matches are 10.4cM and 12.8cM and together they total 23.2 cM, with is just slightly more than the 19.88 we’re looking for.

Harold Me 23andMe Ancestry

You may have noticed already that begin and end segments and matches between vendors even on the same chromosome do vary some.  These two red segments, above, are the most likely candidates to be the missing Ancestry segments, in part, because they are the smallest and their total is near to the 19.88.

GedMatch

At GedMatch, comparing Harold and I at the default of 700 SNPs and 5cM, which is equivalent to the 23andMe threshold, gives us the following:

Harold Me GedMatch at 23andMe Threshold

Next, I ran GedMatch at 500 SNPs and 1cM which is the equivalent of the FTDNA threshold after you have an initial match.

Harold Me GedMatch at FTDNA threshold

Vendor Summary

I’ve put together a vendor summary of our findings.

vendor match summary2

There’s quite a difference between vendors.  More than I expected.

Comparing the Vendors

Given that the GedMatch comparison using the FTDNA thresholds is the most generous in terms of matching segments, let’s compare the three vendors matching segments against the GedMatch matching segments.  Because start and end segments aren’t exactly the same, if any portion of the vendor’s match falls into the GedMatch match segment, I’ve counted it as a match, so in favor of the vendor.

The chart below utilizes the GedMatch to FTDNA matching segments as the foundation, and I’m comparing other vendors’ matches to the GedMatch results.

All Vendor Match Comparison

For purposes of this comparison, ignore WHICH (start, end, cM) column is colored.  I’ve just selected 3 columns and assigned one to color per vendor.  If that segment row is found in that vendor’s comparison, it’s highlighted in that vendor’s color.  So, for the first row, only FTDNA reported chromosome 1, from 44,938,970 to 47,788,153 as a match.  So, therefore, their cell in that row is the only one colored with their color, green.  Looking down to chromosome 5, you can see that both FTDNA and 23andMe show those segments as matches.  Only four chromosome segments are matches using the inferred Ancestry results based on their total cM information.

How Does This Affect Matching

When Ancestry introduced their phasing, as you might recall, a great many matches disappeared.  In essence, what Ancestry has done is relieved you of the problem of figuring out which matches are “solid” by not giving you any option to work with the raw data.

One of the comments that Ancestry has made is that few people who match in a DNA Circles match on the same segments.  In other words, they don’t triangulate, which means that Ancestry is telling us we don’t need to bother with triangulation because it won’t work anyway.  Their commentary becomes more understandable if you eliminate anything but large segments.  Most people who are distantly related are NOT going to match on large segments, and an entire group is not going to match on the same large segment, which is why we desperately need those smaller segments too – along with the raw data to compare.

Of course, because Ancestry provides us with no tools, we can’t see how we match our matches.

The best we can do is to download Ancestry raw data results to either or both Family Tree DNA and GedMatch – but we’ll never see what matches we are missing at Ancestry, which is really sad.

I ran my matches at both Family Tree DNA and at GedMatch for the two segments that Ancestry has apparently removed.

Yes, I have quite a few matches on those segments.  But not beyond what would be expected in terms of the number of people in the data base that I’m being compared to.  I do have some regions that are clearly from endogamous populations, and those areas have pages and pages of matches.  These two segments aren’t like that.

At GedMatch, I ran a triangulation report of that segment of chromosome 5 where I match others at both 23andMe and Family Tree DNA.  And for the really sad part – look at all those A kits, meaning Ancestry – more than half.  Those aren’t small segment matches either.  One triangulation group that includes an Ancestry kit is 14.7cM.  I’m missing those matches at Ancestry unless I happen to match these people on a larger segment that hasn’t been removed by Ancestry’s phasing.

GedMatch Triangulation Chr 5

I decided to check the second segment that Ancestry has removed that shows as a match through23andMe, Family Tree DNA and GedMatch – on chromosome 18.  There are fewer matches on that segment of chromosome 18, not more – so it’s not a pileup area either.  It does triangulate with other people who descend from a common Vannoy ancestor who are not close relatives.

At Family Tree DNA, here are my matches to 5 known Vannoy cousins on chromosome 5 at the FTDNA default threshold.  As you can see, I match two cousins, so we have a triangulation group of 3.

FTDNA Chr 5

Look what happens below, in terms of matching, when the match threshold is lowered.  In addition to several other matches on other chromosomes, I’ve picked up another match on that segment of chromosome 5, which serves to increase that triangulation group to four people on that segment.

FTDNA chr 5 at 1cM

I checked, and indeed, the green, blue and orange cousins do match each other on this segment as well.  Chromosome 18 triangulated too, but with different cousins matching the base person.   The orange cousin is in both triangulation groups.

FTDNA chr 18

Ancestry apparently discarded both of those segments on chromosome 5 and on 18.  Ancestry claims that seldom do people in their DNA Circles match each other on the same segments.  That’s probably true if you’re measuring only very large segments, but we can see from these examples that these are neither pileup regions nor nonmatching segments.  They triangulate between cousins, so they are valid identical by descent matches.

Discussion

I ran this little test as an experiment, but I must admit, I was stunned at the disparity in the matching of the vendors.  There has been a great deal of discussion surrounding the merits of Ancestry’s phasing.  Ancestry claims they are removing non-genealogical matches, as in IBS matches by population in pileup regions.

Based on what we’re seeing above, assuming the inferred discarded segments are accurate (without additional tools, inference is as good as it gets), they’ve pruned the tree too deeply.  That’s really not apparent when you look at your matches at Ancestry for three reasons:

  • Their data base is very large, so you still have a lot of matches
  • You can’t see your segment information
  • The Ancestry matches you do have are only the strongest – so you, proportionally, will have more “solid” matches at Ancestry than at other vendors – which makes people happy who don’t understand the behind the scenes ramifications of what they AREN’T getting and that those matches are not proven to that ancestor – nor is there any way to prove the data without a chromosome browser type of tool.

The smaller the matches reported by the vendors, the further out in time it moves the bar to finding your ancestors – which is why Family Tree DNA has a larger threshold, but still reports the small matching segments.

Let me say that again, in another way.

If you used a hypothetical matching threshold of 50cM for the smallest matching segment, you’re only going to get matches to about second cousins or closer.  Harold and I wouldn’t match with our largest segment being 47cM and we very clearly share a common ancestor. You’d have very few matches (if any) BUT they would all be very solid.  You’d be able to figure out quickly how you are related.  But how would this be useful to genealogy?  You likely already know those people. So this approach is very accurate, but also very restrictive, providing no opportunity to break down those distant brick walls.

If you move the threshold out to Ancestry levels, you’re going to get more matches, but fewer further back in time because the DNA from each contributing ancestor is reduced in each generation.  The majority of your matches will be beyond the 2nd cousin level, because you have a LOT more matches with each generation you go back in time.  Still, your matches will still probably be within a few generations.

At Ancestry, I have only one 3rd cousin DNA tree match, meaning a common ancestor has been identified with that person, about thirty 4th cousins, about a hundred 5th cousins and about thirty distant cousins.  So, you can see that 5th cousins are probably your most likely match and it falls off quickly after that.

If you move the matching threshold out even further, by making it smaller, you’ll have even more matches but many will be distant.  A greater percentage will be identical by chance and identical by population, but you will have some valid matches in those smaller segments.  The caveat is of course that you would have to work to sort the wheat from the chaff, by using triangulation methods.  The common ancestor will likely not be evident and may not be identifiable.  Conversely, the common ancestor may be identifidable…and that may be just what you need to break down that long standing brick wall.  I’ve done that twice now, once on my Younger/Hart line, confirming a wife’s rumored maiden name and one in my Vannoy line, confirming Elijah’s parents through matches to his mother’s Hickerson line.

But, if you don’t have those smaller segments to work with, along with tools, you will NEVER be able to find those elusive distant ancestors using DNA.

The great irony in all of this is that while I was working with the matches to chromosome 5 for this article, I noticed a couple of new matches I hadn’t seen before.  These matches also triangulate, but are from a female line, and now I know that at least part of that segment comes from the Crumley maternal line that married into the Vannoy line.  So, of you think for one minute that these smaller segments aren’t useful or important, think again.

So, the bottom line here is that if you’re interested in the immediate gratification aspect, with no work, but also no ability to utilize DNA segments to find distant ancestors, Ancestry is the one.  Their strong suit is their tree matching and many people are perfectly happy to never go beyond that – replete with incorrect assumptions that this means the ancestral genetic relationship is “proven.”

I currently have about 5400 total matches at Ancestry.  Of those, the day I did this comparison, 152 people matched my DNA and we have a tree match as well, meaning a common ancestor in my tree and their tree has been identified.  Of course, that does not assure that particular ancestor is how our DNA matches, and we can’t confirm that without a chromosome browser.  Still having those matches and matching trees, along with Circles is a wonderful first step.  It’s “feel good” stuff and who doesn’t like feel good.

If you’re interested in the vendor that gives you the most DNA segments to work with along with the tools to do it and therefore the most opportunity, Family Tree DNA, hands down, is the one.  Less feel good but way more potential.

23andMe is someplace in the middle – not easy or intuitive with a difficult communication process resulting in very few people who actually share their matching DNA with you, no feel good stuff, but they have a great matching tool that shows you not only who you match, but who your matches match in common with you as well.

I wish we could combine the best parts of all 3 vendors.  I wrote in detail about the autosomal offerings of all three vendors here.  Today, the best alternative is to test with all three.

Regardless, everyone who tests with any of the 3 vendors (or all of the three vendors) should upload their results to GedMatch where additional tools are provided that aren’t available at any vendor.  Another benefit of GedMatch is that the people there tend to be more serious about genetic genealogy.  The down side is that percentagewise, few people actually do upload their files, so you do still need to test at all of the vendors to achieve maximum matching and benefit from their individual strengths.

Additional tools are also available at www.dnagedcom.com where you will find analysis tools that utilize the matches found at the vendors (via downloads) but provide analysis and display in different ways.

Gedmatch, which works with your raw data and provides comparisons to others, and DNAGedcom.com which downloads your actual match information from the vendors are the great equalizers between vendors today, as much as possible given the vendor matching threshold limits in place internally.  No matter what, the third party tools can’t get more than the vendors give you.

What’s the bottom line?  Fish in all of the ponds, but understand the wide variance in the boundaries and the limitations of each pool.  There is more difference between vendors in ways that might not be initially apparent.

The 1 Million Mark and Effective Matches

one million

Last week, Ancestry.com announced the millionth customer in their autosomal data base.  On January 18th, 23andMe did the same.  I don’t have exact numbers from Family Tree DNA, but they can’t be terribly far behind.  So, let’s look at the effectiveness of these matches at the roughly 1 million mark between the various vendors.

comparison chart

Black bold highlights the vendor’s positive aspects and red bold notes the drawbacks and places where each vendor could stand improvement.  I’ve underlined the two red issues I feel are the most serious.

*1 – Both 23andMe and Ancestry provide communications with others whom you match through internal message systems.  However, you have to request permission at 23andMe with anyone you match to communicate with them, and then additionally to share their DNA.  The 23andMe the 1404 number is how many people I match and the 162 number is the number of people that have accepted communications from me.  Not all of those 162 are sharing DNA.

*2 – At 23andMe, this would be the number of people sharing DNA results with me.  Ancestry has no tools that allow comparison of DNA segments.  At Family Tree DNA this would be all of my matches.

*3 – 23andMe cuts your matches off at 1000 unless you are communicating with your matches or you have an outstanding “introduction sent” request.  Of the 1404 people I match, 138 are sharing genomes, 24 have accepted communications but have not shared genomes, and 12 have declined.  The balance of my 1404 are either those to whom I’ve requested an introduction and they haven’t replied at all or some that I haven’t gotten around to inviting yet.  Ironically, my last of 1404 matches (in percentage of shared DNA order) is my known cousin who would have been purged had we not been sharing genomes.  You don’t have to send introductory invitations to those you match at either Family Tree DNA nor Ancestry and neither of those companies have an arbitrary cutoff, although Ancestry.com did a massive match purge when they implemented phasing.

*4 – At 23andMe, I can request to communicate with all 1404 people I match.  Of those, 162 have agreed to communicate or share genomes.  I can only communicate with those 162 people.  That doesn’t compare very well to either 1040 nor 5481 – and it shows how much genealogical benefit I’ve derived from 23andMe as compared to both Ancestry and Family Tree DNA.

*5 – At Ancestry, a minimum level subscription is required at $49 per year to see matching trees.  Not all participants have trees uploaded, and many trees aren’t public, so are not available for tree matching.  Otherwise, all trees connected to DNA results are included in matching function.

*6 – At Family Tree DNA, testers are encouraged to upload GEDCOM files or create trees in their account, and matching surname hints are given, but no actual ancestor matching in trees is performed.  Each participant must look at the tree of their matches, if provided.

*7 – 23andMe no longer hosts family trees on their site.  They have entered into collaboration with subscription service, MyHeritage.  Family Tree DNA is the only one of the vendors who hosts their own trees and does not require an additional subscription for that service, or for tree matching.

*8 – I have fewer matches at Family Tree DNA now than I did in November of 2014 when I had 1875 matches.  I have submitted a query to Family Tree DNA about this discrepancy but have not yet received a reply.

Commentary

The disparity between the 23andMe and Ancestry match numbers, since both vendors have 1 million autosomal results in their data bases, is suggestive of how many matches may have been pared from my match list at 23andMe.

The number of effective matches that can be usefully utilized, and how they can be utilized, are quite a bit different than the total number of matches implies without further analysis.

Both Family Tree DNA and Ancestry have unique strong points that make them stand out as vendors.

23andMe, since I can only work with or communicate with about 10% of my matches, is the least useful, for me, for genealogy.  I found their health services, which 23andMe is no longer allowed to offer following a dust-up with the FDA, very beneficial.

The tree matches and DNA Circles at Ancestry are very useful, but the fact that Ancestry provides absolutely no tools such as a chromosome browser or the other comparison tools that both 23andMe and Family Tree DNA provide makes Ancestry’s tree matches terribly frustrating eye candy in the candy shop behind a hermetically sealed window we can’t get through.  Tree matches and Circles are suggestive of an ancestral connection, but without comparison and triangulation tools, your match to an individual could be through a different, potentially unknown, line, and you have no tools at Ancestry to confirm or deny.  People are left to assume that the tree matches and Circles are proof, and unfortunately, they do in droves.

Thankfully, Family Tree DNA accepts transfers from Ancestry, V3 chip transfers from 23andMe (not the V4 chip since Dec. 2013) and GedMatch accepts files from all 3 vendors.  Those are the only avenues to actually compare the DNA of those who tested at Ancestry to triangulate and prove ancestral matches.

The great news in all of this is that more than 1 million people have tested, and probably more than two million in total – although there is clearly some overlap between vendors.  With every person that tests and that we match in one place or another, it increases our odds as genealogists to confirm our genealogy or break through those pesky brick walls.

Footnote:  The prices for the tests are the same, at $99, unless a sale is taking place at one of the vendors.  Both 23andMe and Ancestry also sell the aggregated anonymized DNA data for other purposes.  Both 23andMe and Ancestry will request that you sign (digitally authorize by clicking a box) an informed consent agreement for your non-anonymized (or less anonymized) data to be utilized or sold as well.  Family Tree DNA is the only one of these three firms that does not sell your DNA data in any form.

DNA Testing Strategy for Adoptees and People with Uncertain Parentage

Adoptees aren’t the only people who don’t know who their parents are.  There are many people who don’t know the identity of one of their two parents…and it’s not always the father.  Just this week, I had someone who needed to determine which of two sisters was her mother.  Still, the “who’s your Daddy” crowd, aside from adoptees, is by far the largest.

The DNA testing strategy for both of these groups of people is the same, with slight modifications for male or female. Let’s take a look.

Males have three kinds of DNA that can be tested and then compared to other participants’ results.  The tests for these three kinds of DNA provide different kinds of information which is useful in different ways.  For example, Y DNA testing may give you a surname, if you’re a male, but the other two types of tests can’t do that, at least not directly.

Females only have two of those kinds of DNA that can be tested.  Females don’t have a Y chromosome, which is what makes males male genetically.

adopted pedigree

If you look at this pedigree chart, you can see that the Y chromosome, in blue, is passed from the father to the son, but not to daughters.  It’s passed intact, meaning there is no admixture from the mother, who doesn’t have a Y chromosome, because she is female.  The Y chromosome is what makes males male.

The second type of DNA testing is mitochondrial, represented by the red circles.  It is passed from the mother to all of her children, of both genders, intact – meaning her mitochondrial DNA is not admixed with the mtDNA of the father.  Woman pass their mtDNA on to their children, men don’t.

Therefore when you test either the Y or the mtDNA, you get a direct line view right down that branch of the family tree – and only that direct line on that branch of the tree.  Since there is no admixture from spouses in any generation, you will match someone exactly or closely (allowing for an occasional mutation or two) from generations ago.  Now, that’s the good and the bad news – and where genealogical sleuthing comes into play.

On the chart above, the third kind of DNA testing, autosomal DNA, tests your DNA from all of your ancestors, meaning all of those boxes with no color, not just the blue and red ones, but it does include the blue and red ancestors too.  However, autosomal DNA (unlike Y and mtDNA) is diluted by half in each generation, because you get half of your autosomal DNA from each parent, so only half of the parents DNA gets passed on to each child.

Let’s look at how these three kinds of DNA can help you identify your family members.

Y DNA

Since the Y DNA typically follows the paternal surname, it can be extremely helpful for males who are searching for their genetic surname.  For example, if your biological father’s surname is Estes, assuming he is not himself adopted or the product of a nonpaternal event (NPE) which I like to refer to as undocumented adoptions, his DNA will match that of the Estes ancestral line.  So, if you’re a male, an extremely important test will be the Y DNA test from Family Tree DNA, the only testing company to offer this test.

Let’s say that you have no idea who your bio-father is, but when your results come back you see a preponderance of Estes men whom you match, as well as your highest and closest matches being Estes.

By highest, I mean on the highest panel you tested – in this case 111 markers.  And by closest, I mean with the smallest genetic distance, or number of mutations difference.  On the chart below, this person matches only Estes males at 111 markers, and one with only 1 mutation difference (Genetic Distance.)  Please noted that I’ve redacted first names.

Hint for Mr. Hilbert, below – there is a really good chance that you’re genetically Estes on the direct paternal side – that blue line.

Estes match ex

The next step will be to see which Estes line you match the most closely and begin to work from there genealogically.  In this case, that would be the first match with only one difference.  Does your match have a tree online?  In this case, they do – as noted by the pedigree chart icon.  Contact this person.  Where did their ancestors live?  Where did their descendants move to?  Where were you born?  How do the dots connect?

The good news is, looking at their DNA results, you can see that your closest match has also tested autosomally, indicated by the FF icon, so you can check to see if you also match them on the Family Finder test utilizing the Advanced Matching Tool.  That will help determine how close or distantly related you are to the tester themselves.  This gives you an idea how far back in their tree you would have to look for a common ancestor.

Another benefit is that your haplogroup identifies your deep ancestral clan, for lack of a better word.  In other words, you’ll know if your paternal ancestor was European, Asian, Native American or African – and that can be a hugely important piece of information.  Contrary to what seems intuitive, the ethnicity of your paternal (or any) ancestor is not always what seems evident by looking in the mirror today.

Y DNA – What to order:  From Family Tree DNA, the 111 marker Y DNA test.  This is for males only.  Family Tree DNA is the only testing company to provide this testing.  Can you order fewer markers, like 37 or 67?  Yes, but it won’t provide you with as much information or resolution as ordering 111 markers.  You can upgrade later, but you’ll curse yourself for that second wait.

FTDNA Y

Mitochondrial DNA

Males and females both can test for mitochondrial DNA.  Matches point to a common ancestor directly up the matrilineal side of your family – your mother, her mother, her mother – those red circles on the chart.  These matches are more difficult to work with genealogically, because the surnames change in every generation.  Occasionally, you’ll see a common “most distant ancestor” between mitochondrial DNA matches.

Your mitochondrial DNA is compared at three levels, but the most accurate and detailed is the full sequence level which tests all 16,569 locations on your mitochondria.  The series of mutations that you have forms a genetic signature, which is then compared to others.  The people you match the most closely at the full sequence level are the people with whom you are most likely to be genealogically related to a relevant timeframe.

You also receive your haplogroup designation with mitochondrial DNA testing which will place you within an ethnic group, and may also provide more assistance in terms of where your ancestors may have come from.  For example, if your haplogroup is European and you match only people from Norway….that’s a really big hint.

Using the Advanced Matching Tool, you can also compare your results to mitochondrial matches who have taken the autosomal Family Finder test to see if you happen to match on both tests.  Again, that’s not a guarantee you’re a close relative on the mitochondrial side, but it’s a darned good hint and a place to begin your research.

Mitochondrial DNA – What to Order:  From Family Tree DNA, the mitochondrial full sequence test.  This is for males and females both.  Family Tree DNA is the only company that provides this testing.

FTDNA mtDNA

Autosomal DNA

Y and mitochondrial DNA tests one line, and only one line – and shoots like a laser beam right down that line, telling you about the recent and deep history of that particular lineage.  In other words, those tests are deep and not wide.  They can tell you nothing about any of your other ancestors – the ones with no color on the pedigree chart diagram – because you don’t inherit either Y or mtDNA from those ancestors.

Autosomal DNA, on the other hand tends to be wide but not deep.  By this I mean that autosomal DNA shows you matches to ancestors on all of your lines – but only detects relationships back a few generations.  Since each child in each generation received half of their DNA from each parent – in essence, the DNA of each ancestor is cut in half (roughly) in each generation.  Therefore, you carry 50% of the DNA of your parents, approximately 25% of each grandparent, 12.5% of the DNA of each great-grandparent, and so forth.  By the time you’re back to the 4th great-grandparents, you carry only about 1% of the DNA or each of your 64 direct ancestors in that generation.

What this means is that the DNA testing can locate common segments between you and your genetic cousins that are the same, and if you share the same ancestors,  you can prove that this DNA in fact comes from a specific ancestor.  The more closely you are related, the more DNA you will share.

Another benefit that autosomal testing provides is an ethnicity prediction.  Are these predictions 100% accurate?  Absolutely not!  Are they generally good in terms of identifying the four major ethnic groups; African, European, Asian and Native American?  Yes, so long at the DNA amounts you carry of those groups aren’t tiny.  So you’ll learn your major ethnicity groups.  You never know, there may be a surprise waiting for you.

FTDNA myOrigins

The three vendors who provide autosomal DNA testing and matching all provide ethnicity estimates as well, and they aren’t going to agree 100%.  That’s the good news and often makes things even more interesting.  The screen shot below is the same person at Ancestry as the person above at Family Tree DNA.

Ancestry ethnicity

If you’re very lucky, you’ll test and find an immediate close match – maybe even a parent, sibling or half-sibling.  It does happen, but don’t count on it.  I don’t want you to be disappointed when it doesn’t happen.  Just remember, after you test, your DNA is fishing for you 24X7, every single hour of every single day.

If you’re lucky, you may find a close relative, like an uncle or first cousin.  You share a common grandparent with a first cousin, and that’s pretty easy to narrow down.  Here’s an example of matching from Family Tree DNA.

FTDNA close match

If you’re less lucky, you’ll match distantly with many people, but by using their trees, you’ll be able to find common ancestors and then work your way forward, based on how closely you match these individuals, to the current.

Is that a sometimes long process?  Yes.  Can it be done?  Absolutely.

If you are one of the “lottery winner” lucky ones, you’ll have a close match and you won’t need to do the in-depth genealogy sleuthing.  If you are aren’t quite as lucky, there are people and resources to help you, along with educational resources.  www.dnaadoption.com provides tools and education to teach you how to utilize autosomal DNA tools and results.

Of course, you won’t know how lucky or unlucky you are unless you test.  Your answer, or pieces of your answer, may be waiting for you.

Unlike Y and mtDNA testing, Family Tree DNA is not the only company to provide autosomal of testing, although they do provide autosomal DNA testing through their Family Finder test.

There are two additional companies that provide this type of testing as well, 23andMe and Ancestry.com.  You should absolutely test with all three companies, or make sure your results are in all three data bases.  That way you are fishing in all of the available ponds directly.

If you have to choose between testing companies and only utilize one, it would be a very difficult choice.  All three have pros and cons.  I wrote about that here.  The only thing I would add to what I had to say in the comparison article is that Family Tree DNA is the only one of the three that is not trying to obtain your consent to sell your DNA out the back door to other entities.  They don’t sell your DNA, period.  You don’t have to grant that consent to either Ancestry or 23andMe, but be careful not to click on anything you don’t fully understand.

Family Tree DNA accepts transfers of autosomal data into their data base from Ancestry.  They also accept transfers from 23andMe if you tested before December of 2013 when 23andMe reduced the number of locations they test on their V4 chip

Autosomal DNA:  What to Order

Ancestry.com’s DNA product at http://www.ancestry.com – they only have one and it’s an autosomal DNA test

23andMe’s DNA product at http://www.23andMe.com – they only have one and it’s an autosomal DNA test

Family Tree DNA – either transfer your data from Ancestry or 23andMe (if you tested before December 2013), or order the Family Finder test. My personal preference is to simply test at Family Tree DNA to eliminate any possibility of a file transfer issue.

FTDNA FF

Third Party Autosomal Tools

The last part of your testing strategy will be to utilize various third party tools to help you find matches, evaluate and analyze results.

GedMatch

At GedMatch, the first thing you’ll need to do is to download your raw autosomal data file from either Ancestry or Family Tree DNA and upload the file to www.gedmatch.com.  You can also download your results from 23andMe, but I prefer to utilize the files from either of the other two vendors, given a choice, because they cover about 200,000 additional DNA locations that 23andMe does not.

Ancestry.com provides you with no tools to do comparisons between your DNA and your matches.  In other words, no chromosome browser or even information like how much DNA you share.  I wrote about that extensively in this article, and I don’t want to belabor the point here, other than to say that GedMatch levels the playing field and allows you to eliminate any of the artificial barriers put in place by the vendors.  Jim Bartlett just wrote a great article about the various reasons why you’d want to upload your data to Gedmatch.

GedMatch provides you with many tools to show to whom you are related, and how.  Used in conjunction with pedigree charts, it is an invaluable tool.  Now, if we could just convince everyone to upload their files.  Obviously, not everyone does, so you’ll still need to work with your matches individually at each of the vendors and at GedMatch.

GedMatch is funded by donations or an inexpensive monthly subscription for the more advanced tools.

DNAGEDCOM.com

Another donation based site is http://www.dnagedcom.com which offers you a wide range of analytical tools to assist with making sense of your matches and their trees.  DNAGEDCOM works closely with the adoption community and focuses on the types of solutions they need to solve their unique types of genealogy puzzles.  While everyone else is starting in the present and working their way back, adoptees are starting with the older generations and piecing them together to come forward to present.  Their tools aren’t just for adoptees though.  Tools such as the Autosomal DNA Segment Analyzer are great for anyone.  Visit the site and take a look.

Third Party Y and Mitochondrial Tools – YSearch and MitoSearch

Both www.ysearch.org and www.mitosearch.org are free data bases maintained separately from Family Tree DNA, but as a courtesy by Family Tree DNA.  Ysearch shows only a maximum of 100 markers for Y DNA and Mitosearch doesn’t show the coding region of the mitochondrial DNA, but they do allow users to provide their actual marker values for direct comparison, in addition to other tools.

Furthermore, some people who tested at other firms, when other companies were doing Y and mtDNA testing, have entered their results here, so you may match with people who aren’t matches at Family Tree DNA.  Those other data bases no longer exist, so Ysearch or Mitosearch is the only place you have a prayer of matching anyone who tested elsewhere.

You can also adjust the match threshold so that you can see more distant matches than at Family Tree DNA.  You can download your results to Ysearch and Mitosearch from the bottom of your Family Tree DNA matches page.

Mitosearch upload

Answer the questions at Mito or Ysearch, and then click “Save Information.”  When you receive the “500” message that an error has occurred at the end of the process, simply close the window.  Your data has been added to the data base and you can obtain your ID number by simply going back to your match page at Family Tree DNA and clicking on the “Upload to Ysearch” or Mitosearch link again on the bottom of your matches page.  At that point, your Y or mitosearch ID will be displayed.  Just click on “Search for Genetic Matches” to continue matching.

Get Going!

Now that you have a plan, place your orders and in another 6 to 8 weeks, you’ll either solve the quandry or at least begin to answer your questions.  Twenty years ago you couldn’t have begun to unravel your parentage using DNA.  Now, it’s commonplace.  Your adventure starts today.

Oh, and congratulations, you’ve just become a DNA detective!

I wish you success on your journey – answers, cousins, siblings and most importantly, your genetic family.  Hopefully, one day it will be you writing to me telling me how wonderful it was to meet your genetic family for the first time, and what an amazing experience it was to look across the dinner table and see someone who looks like you.

Why Autosomal Response Rate REALLY DOES Matter

In my recent article “Autosomal DNA 2015 – Which Test is the Best?,” one of the comparison items between vendors I mentioned is response rate.  Specifically, I said, in reference to 23andMe, “Very low match response rate to inquiries.  Positive response is required to see matching DNA segments.”

This has generated some commentary, but based on the nature of the comments, both in terms of blog comments and private e-mails, I can tell that many people don’t understand why response rate matters at 23andMe.  On the other hand, some regular users of all 3 vendors felt I didn’t go far enough in explaining the difference and why response rate at 23andMe matters so much.

I’m going to see if I can make this issue a bit more clear.  Response rate really does matter and it’s not just whining!

apples oranges

At 23andMe YOU CAN’T SEE MATCH INFORMATION OR DO ANY DNA COMPARISON WITHOUT A POSITIVE RESPONSE FROM THOSE YOU MATCH.  In other words, they must reply in the affirmative – that they want to communicate with you AND that they want to share DNA results.  Otherwise, you can do nothing.

This is a process not required by either Family Tree DNA or Ancestry.  So, out the door, there is a very big difference.

At Family Tree DNA, you can see everything available WITHOUT additional correspondence, so while a response from a match would be nice, it’s not essential to being able to compare their DNA, see who you match in common, see their tree, if posted, find your common surnames, or perform any other function provided by the vendor.

At Ancestry.com, WITH a subscription, you can see your matches, their trees (if not private) and DNA Circles with no additional correspondence.  The only time you need to correspond with someone is if their tree is private or they don’t post a tree.

The operative words here are want and need.  At 23andMe, you absolutely positively NEED a positive response from each and every match (both authorization to communicate AND authorization to share DNA results) BEFORE you can DO anything.

So, comparatively speaking, a low response rate at 23andMe means that you’re only going to see a small fraction of your matches that are showing, while a low response rate at the other vendors is an irritant and comes after you’ve utilized the vendor’s tools and then asked your match for additional information.  In other words, no response at Family Tree DNA or Ancestry is not a barrier to playing.  At 23andMe, you’re dead in the water if your matches don’t respond.

In essence, 23andMe requires three authorizations to be able to see your matches DNA information: the original authorization to test, authorization to communicate and authorization to “share” DNA results.

With both Family Tree DNA and Ancestry, one authorization, when you initially test, is all you need – although the tools and approach of these two vendors are very different as pointed out in the original article.

So, as you can see, the response rate at Family Tree DNA and Ancestry really isn’t essential to utilizing the tools, but it’s another matter entirely at 23andMe – so we’re not comparing apples to apples.

So, let’s look at the real effects of 23andMe’s authorization policy.

At 23andMe

At 23andMe, this is what you get, out of the box.  The person’s account I’m using for this first graphic tested for two purposes and is not interested in genealogical contact, so this is an “untouched” account, except that I’ve redacted the names, if showing, in blue to the left.  Looks good – all those matches, until you realize you can’t DO anything without contacting each and every single match.

23andme untouched

What isn’t obvious is that you can’t COMPARE your DNA or information with any of these people WITHOUT sending an introduction request.  In addition, they ALSO must authorizing DNA sharing.  And by the way, an introduction request and DNA sharing are NOT one and the same thing.  You can see the names of public matches, who have pre-authorized communications, but you cannot compare DNA with them.  You can’t even see the names of other (nonpublic) matches until you send an introduction request to them and they reply in the affirmative.  Those are the accounts above that just say “male” with no blue partially redacted name above them.

If you click on “Send an introduction,” here are your options.

23andMe intro request

You can request an intro and genome sharing in one message, but that doesn’t mean they’ll accept both nor does it mean that someone will send you a request for both.

This is what an introduction request looks like to the receiver.

23andMe contact request

Now, an introduction request only allows you to talk to your match.  If they do not ask for, or authorize genome sharing, next, you have to request to share your DNA results – and they also have to reply in the affirmative to that request too.

Not intuitively obvious you say?  Right!

Here’s the process to request to share genomes.

23andme dna share request

And here’s the reply step to authorize genome sharing.

23andme dna share authorization crop

Is it any wonder the response rate is low?

So, as you can see, just being able to see that you have a match is not the same thing as being able to utilize the information.  With Family Tree DNA and Ancestry, you can immediately utilize the information from all of your matches to the full extent of that vendor’s offerings.

At Family Tree DNA

At Family Tree DNA, here is what you see out the gate (full names redacted.)

Family Tree DNA out the gate

No contact request needed, no separate authorization to share DNA and no subscription required to see your matches, to compare DNA, to see who you match in common, to see their trees (if provided) or to see your matching surnames.  The little dropdown box under each person provides additional options.

You don’t NEED to contact your matches for anything.  You may WANT to contact them for genealogy information, especially if they have not uploaded or created trees.

At Ancestry – WITH Subscription

At Ancestry.com, to see all three available DNA related features, your matches, their trees (if provided and if public) and DNA Circles, you must have a subscription.  Ancestry offers a minimal subscription for $49, per year, for this purpose or a standard subscription covers DNA functionality as well.  You must have a subscription to see your matches trees and your DNA Circles.

Here is what your Ancestry match page looks like.

Ancestry with subscription

You don’t NEED to contact your matches to view results.  You may WANT to contact those you match and if their tree is private, you will have to contact them to request to see the tree or for the identity of your common ancestor if you have a shakey leaf.

Comparative Numbers

So, let’s look at this comparatively, for my accounts at the three vendors.

23andMe Family Tree DNA Ancestry (with subscription)
Total Number of Matches 1373 2100 3950
Number of Matches I can see without special approvals (meaning a match response required) 0 (0%) 2100 (100%) 3950 (100%)
At 10% response rate, number of effective matches 137 (10%) 2100 (100%) 3950 (100%)
At 10% response rate, DNA accounts available to compare DNA 10% or 137  accounts 100% or 2100 accounts 0% (no chromosome browser)

This shows, in black and white, why a low response rate at 23andMe is so devastating.  The percent of people whose DNA you can see equals the response rate at 23andMe.  So if you have 1000 matches at 23andMe, but you only have a 10% response rate, it’s the same as having only 100 functional matches – because the rest are entirely unavailable to you – well except for the fact that they sit there and stare at you mockingly.

If one has a 10% response rate at 23andMe, and all of those responses are positive, and all authorize BOTH communication and DNA sharing, you are still only seeing 10% of the matches listed.  So, 1000 matches at 23andMe is not at all the same as 1000 matches at Family Tree DNA or Ancestry.

At Family Tree DNA, all of your match accounts are immediately available to you for viewing, communicating and comparison.

At Ancestry, you can see all of your matches (with a subscription), but you can’t compare the matching DNA because Ancestry offers no chromosome browser.

The Meat

The meat of genetic genealogy is comparing your actual segments to your matches.  So, let’s look at some real numbers.

I send a custom request to each of my matches at 23andMe and have been doing so since the product was introduced.

Looking at my top 100 matches, let’s see how many authorized sharing.

In a way, this is skewing the results, just so you know, because many of these matches are relatives who I recruited to test initially.  Plus I’ve worked on my closest matches at 23andMe much harder than my more distant matches, so this is an absolute BEST CASE scenario for the 23andMe numbers.  My actual response rate is about 10% for all matches.

At 23andMe, of my closest 100 matches, several of which are close family, 22 of my matches are sharing, one has declined and the rest are in limbo where I’ve sent an invitation and they have not responded. It’s interesting to note that of those 100, 23 are “public” which means that the intro step can be skipped, but they still have to be invited to share genomes.

Number of my 100 closest matches I can see:

23andMe Family Tree DNA Ancestry
Number of 100 closest matches I can see 22 (22%) 100 (100%) 100 (100%)
Extrapolated by % to entire match total 302 of 1373 2100 of 2100 3950 of 3950

23andMe said that existing trees would be available until May 1, 2015, but I can find no trees attached to any of my matching 23andMe accounts now, although there never were many.

Number of trees I can see:

23andMe Family Tree DNA Ancestry
Number of trees I can see 0 (0%) 33 (33%) 66 (66%)*
Extrapolated by % to match total 0 of 1373 693 of 2100 2607 of 3950

*The balance of Ancestry trees are 20 matches that have no trees and 14 that have private trees.  Twenty of the 66 have common ancestors, but of those, 6 are private trees.

Number of people with whom I can compare DNA segments in chromosome browser:

23andMe Family Tree DNA Ancestry
Number of people I can compare DNA 22 (22%) 100 (100%) 0 (0%) (no chromosome browser tool)
Extrapolated by % to match total 302 of 1373 2100 of 2100 0 of 3950

I hope these examples help make it clear why response rate really is an important factor – unfortunately – and why a response rate discussion about Family Tree DNA and Ancestry does not have the same meaning as a response rate discussion about 23andMe.

One of the best things 23andMe could do would be to get rid of the convoluted DNA authorization courtship Macarena dance.  There is no dance instructor, people don’t discover that they need to do it until after they test, and many people simply don’t understand, don’t bother or give up.  If 23andMe isn’t going to get rid of it, the LEAST they could do is to make it easy and step you through the process.  I don’t know who benefits from this, but I guarantee you, it’s not the genealogy consumer.

macarena

Autosomal DNA 2015 – Which Test is the Best?

One of the questions most often asked today is which autosomal DNA test, or testing company, is the best, meaning Ancestry, 23andMe or Family Tree DNA.

The answer is often that it varies depending on your goals, individual priorities and budget.  As with all things, circumstances with the vendors change over time.  They offer new products, change features and overall, sometimes their actions and choices make them more or less valuable and attractive to the consumer.

This article reflects my opinions about what is good, and bad, at each vendor, today, in February 2015, and what they do best and worst.  I am reviewing them in alphabetical order.

23andMe

Best Feature

  • Ability to download matching information about who your matches match that you match as well, along with common matching DNA segments, allowing direct triangulation.

23andme best feature

In the example above, you can select the profile of any person you match and match  against the profile of anyone else you match, showing you the common DNA segments of all parties.

Good Features

  • Chromosome Browser
  • Ethnicity feature tends to report minority Native and African when other companies sometimes fail to do so.
  • Ethnicity painted on chromosome segments.
  • Matching names provided in order of frequency found – of course this assumes that the matches have entered a list of family surnames, which isn’t often the case.
  • Y and mitochondrial DNA haplogroup estimate provided.

Not So Good

  • Trees – were horrible before. 23andMe has recently partnered with MyHeritage which will require a subscription if your tree is larger than 250 individuals. The jury is still out on this but the initial release has been rocky and appears untested.
  • Most of their customers are not genealogists and are not interested or know little about their genealogy. Fortunately, serious genealogists often test with multiple companies so you’re likely to catch them at either Family Tree DNA or at Ancestry.
  • Very low match response rate to inquiries.  Positive response is required to see matching DNA segments.
  • Must communicate through internal message system.
  • Unfriendly website – difficult to find information.
  • Big Pharm alliances, contracts and medical patents – and your DNA is included one way or another, individually or aggregated, depending on the level of your authorization.
  • Corporate focus is on medical and not genealogical.
  • Customer support is poor, slow and often never replies.
  • Limit of roughly 1000 matches, at which point your matches begin to be trimmed. You can retain more if you have established communications with people. I have over 1200 matches today, but I don’t know how many I have lost. This can make your effective matching threshold much higher than their published number by virtue of the fact that your smallest matches are forever being trimmed after you reach the 1000 match threshold.
  • Spit kit versus swab kit.
  • Cannot adjust matching threshold.
  • V4 chip precludes data transfer to Family Tree DNA
  • Test not available worldwide, meaning data base is not worldwide.  Also not available in NY or MD.

Worst Feature

  • Horribly cumbersome and confusing multiple introductory and authorization/acceptance hurdles cause many people to not contact, communicate with and authorize sharing with most of their matches. I wrote about this here.

 

Ancestry.com

Best Feature

  • The shakey leaf hints that show you who, of your DNA matches, also share a common ancestor in your pedigree chart. This drastically reduces the amount of initial footwork you need to do.

shakey leaf

Good Features

  • The size of their data base increases likelihood of matching.
  • DNA Circles provides additional evidence of ancestral connection.
  • They are a genealogy, not a medically focused company.
  • Provides list and links to matching surnames on matches trees, even when no common ancestor is identified.
  • Clean, easy to use interface, although major changes have been announced and I have no idea whether that will be a positive or negative

Not So Good

  • Some people have private trees which means they can see your match information, including a common ancestor if there is one, but you cannot see theirs.
  • Ancestry ethnicity sometimes finds minority amounts of admixture, but can also be significantly incorrect on majority ancestry, so it’s difficult to have confidence in the consistency of results.
  • Subscription required (starting at $49) to see matches/circle members which may not be fully understood before testing by consumers. In my case, I have a full subscription, so it’s a moot point, but that is not the case with everyone and it can be an unwelcome surprise.
  • Ancestry’s consent allows them to sell anonymized results to buyers, including Big Pharm, should they choose to do so. As of October 2014 when I visited Ancestry as part of DNA Day, they stated that they had not sold any DNA data at that time.
  • Communication is only through internal message system.
  • Spit kit versus swab kit.
  • Customer service is often uneducated about genetic genealogy in general, although they are responsive.
  • Combination of matching and Circles leads people to believe that these are confirmed genetic matches to that particular line, even though Ancestry states otherwise, if one reads the text.
  • DNA is an auxiliary tool and not a primary or priority corporate focus.
  • Corporate history shows lack of commitment to DNA and to clients who tested – meaning their on-again-off-again DNA history the destruction of the Y and mtDNA data bases in October 2013.
  • Academic phasing may have trimmed real matches.
  • Test not available worldwide, meaning data base is not worldwide, although Ancestry has just announced availability in the UK and Ireland.
  • Y and mitochondrial DNA ignored.

Worst Feature

  • No chromosome browser or equivalent type of tool or tools. I can’t state this strongly enough and it is a HUGE negative and requires that you transfer your results to either Family Tree DNA or to Gedmatch where you do have tools.

 

Family Tree DNA

Best Feature

  • Full service genetic genealogy company – focused on genetic genealogy.

ftdna best feature

Good Features

  • Accepts transfers from Ancestry and V3 chip from 23andMe
  • Partnership with National Geographic for research.
  • Chromosome browser which includes in-common-with feature, search by surname and search by ancestral name.
  • Matching Matrix individually and within projects for administrators.
  • Projects and the ability within projects with advanced matching to see everyone you match autosomally within that project.
  • Match names and e-mails provided – not forced to utilize an internal messaging system.
  • Consent signed when ordering test is all that is needed for full matching and all features.
  • Does common surname matching with all matches – bolding the results.
  • Matching attempts to take highly endogamous populations into consideration.
  • Includes access to other genetic genealogy tools like various levels of Y and mtDNA tests.
  • Data base includes results for all tests, in one place, and resulting matches show Y and mtDNA haplogroups if that test has also been taken.
  • Searches can include multiple types of test results, like everyone who matches both the mtDNA and the Family Finder test.
  • Archives DNA for 25 years, allowing upgrades to be done on order without re-swabbing if DNA is adequate and viable.
  • Testing performed in in-house lab.
  • Project administrator liaison provided.
  • Educational webinars for general genetic genealogy education and new product/feature releases. Archived webinars available on demand.
  • Project administrator conference annually for the past decade.
  • New features regularly released.
  • Swab kit versus spit kit.
  • Responsive to customer and project administrator needs and requests.
  • Their customers more likely to be serious genealogists versus someone who tested initially for medical information (at 23andMe before December 2013) or impulse buyers.
  • They do not sell and do not request consent to sell your personal or aggregated data to outside buyers. If your DNA data is ever requested for an academic research project, you will be individually contacted for consent.
  • No subscription that increases actual cost of utilizing the test results.
  • Available worldwide (unless illegal in the location, like France.)

Not So Good

  • Cannot see if your matches also match each other on a specific segments, so cannot directly triangulate.
  • Cannot adjust matching threshold for initial match, but can after initial match.
  • Ethnicity often does not pick up small amounts of minority admixture found by other vendors and at Gedmatch.

Worst Feature

  • Trees are difficult to use.

Recommendations

1. In light of the above, my recommendation for autosomal DNA testing for genealogy if you can take only one test, order the Family Finder test with Family Tree DNA. They are unquestionably committed to genetic genealogy, have the most comprehensive set of tools, including a chromosome browser and other matching tools, and are overall the best company. The Family Finder test costs $99, unless you purchase when it’s on sale or have a coupon. (Current coupon code for $15 off is 15for15.)

2. If you can test with two companies, test with Family Tree DNA and Ancestry.com. You can do this by testing with Ancestry.com and transferring your results to Family Tree DNA,  This approach costs about $187 total: to test at Ancestry ($99), for the first year basic subscription at Ancestry to see all your matching results ($49) if you aren’t already a subscriber, then to transfer the results to Family Tree DNA (free) and unlock the results ($39) unless you find 4 more people to transfer and then the unlock is free.  Note that you will still need to swab to obtain the genealogy benefits of Y and mtDNA testing if you choose to take those tests in addition – and I hope you will because those are very valuable genealogy tools too and not available at the other vendors.

3. In my opinion, 23andMe has become a distant third in DNA testing due to their floundering and lack of commitment in the genealogy market-space, their prohibitively difficult introduction system that requires individual approvals for communicating and then for sharing of DNA (meaning matching) for each person you match, their recent alliance with Big Pharm, and their continuing lack of responsiveness to requests for genealogy enhancements. Lastly, you can no longer transfer your results from 23andMe to Family Tree DNA because 23andMe moved to the v4 chip (in December of 2013) which reduced the number of SNPs tested from about 900,000 to about 600,000, making the results incompatible with Family Tree DNA. However, just because they are third doesn’t mean you shouldn’t test there if you are really serious and want to fish in all of the ponds. It’s just the third choice if you can’t test at all three.

Judy Russell, The Legal Genealogist just wrote an article, 2015, Most bang for the DNA buck, which I suggest you read as well.  She makes some very good points, although our approach is a bit different.  But then again, I’d expect that.  I’ve spent my life doing “analytical” types of things and she has spent her life doing “lawyery” types of things, and there is nothing better than two perspectives to draw from.

The Future

It will be interesting to see what the landscape looks like a year, 2 and 5 years from now.  I think the X-prize (pardon the pun) will go to the company or companies that provide comprehensive tools and make genetic genealogy as easy and productive as possible – for both the beginner and the advanced user.  No small feat – that’s for sure!

Cilantro – Love It or Hate It

This falls into the “just for fun” category.

I received this e-mail from 23andMe a few weeks ago.

cilantro

I found this interesting, so I clicked on the “see my report” link.

cilantro2

I don’t like cilantro, but it doesn’t taste like soap to me, just bitter.

cilantro3

This genetic connection was reported in two papers written by 23andMe and is found on two different genetic locations, one described above, and one, below.

cilantro4

On this same page, my family and cousins were listed by group of who carries which version of the gene. I found that interesting, so I decided to ask and see how reality stacked up to genetic prediction.

I texted my kids to see if they liked Cilantro, and the fact that they were excited, thinking I had found a new recipe to try, gave me the answer.  They both do.  I don’t.  Let’s see how this stacks up to those two marker values and their cumulative predictions.

Rs2741762 Rs3930459 Actually Likes or Dislikes
Son Typical odds like/dislike Higher odds of disliking Likes
Daughter Typical odds like/dislike Typical odds like/dislike Likes
Me Lower odds of disliking Higher odds of disliking Dislikes

Looking at this information, my son should probably dislike Cilantro, my daughter would have normal odds of liking or disliking it, and if I averaged, I’d fall in the middle too, but that’s not how it worked out in real life.

2014 Top Genetic Genealogy Happenings – A Baker’s Dozen +1

It’s that time again, to look over the year that has just passed and take stock of what has happened in the genetic genealogy world.  I wrote a review in both 2012 and 2013 as well.  Looking back, these momentous happenings seem quite “old hat” now.  For example, both www.GedMatch.com and www.DNAGedcom.com, once new, have become indispensable tools that we take for granted.  Please keep in mind that both of these tools (as well as others in the Tools section, below) depend on contributions, although GedMatch now has a tier 1 subscription offering for $10 per month as well.

So what was the big news in 2014?

Beyond the Tipping Point

Genetic genealogy has gone over the tipping point.  Genetic genealogy is now, unquestionably, mainstream and lots of people are taking part.  From the best I can figure, there are now approaching or have surpassed three million tests or test records, although certainly some of those are duplicates.

  • 500,000+ at 23andMe
  • 700,000+ at Ancestry
  • 700,000+ at Genographic

The organizations above represent “one-test” companies.  Family Tree DNA provides various kinds of genetic genealogy tests to the community and they have over 380,000 individuals with more than 700,000 test records.

In addition to the above mentioned mainstream firms, there are other companies that provide niche testing, often in addition to Family Tree DNA Y results.

In addition, there is what I would refer to as a secondary market for testing as well which certainly attracts people who are not necessarily genetic genealogists but who happen across their corporate information and decide the test looks interesting.  There is no way of knowing how many of those tests exist.

Additionally, there is still the Sorenson data base with Y and mtDNA tests which reportedly exceeded their 100,000 goal.

Spencer Wells spoke about the “viral spread threshold” in his talk in Houston at the International Genetic Genealogy Conference in October and terms 2013 as the year of infection.  I would certainly agree.

spencer near term

Autosomal Now the New Normal

Another change in the landscape is that now, autosomal DNA has become the “normal” test.  The big attraction to autosomal testing is that anyone can play and you get lots of matches.  Earlier in the year, one of my cousins was very disappointed in her brother’s Y DNA test because he only had a few matches, and couldn’t understand why anyone would test the Y instead of autosomal where you get lots and lots of matches.  Of course, she didn’t understand the difference in the tests or the goals of the tests – but I think as more and more people enter the playground – percentagewise – fewer and fewer do understand the differences.

Case in point is that someone contacted me about DNA and genealogy.  I asked them which tests they had taken and where and their answer was “the regular one.”  With a little more probing, I discovered that they took Ancestry’s autosomal test and had no clue there were any other types of tests available, what they could tell him about his ancestors or genetic history or that there were other vendors and pools to swim in as well.

A few years ago, we not only had to explain about DNA tests, but why the Y and mtDNA is important.  Today, we’ve come full circle in a sense – because now we don’t have to explain about DNA testing for genealogy in general but we still have to explain about those “unknown” tests, the Y and mtDNA.  One person recently asked me, “oh, are those new?”

Ancient DNA

This year has seen many ancient DNA specimens analyzed and sequenced at the full genomic level.

The year began with a paper titled, “When Populations Collide” which revealed that contemporary Europeans carry between 1-4% of Neanderthal DNA most often associated with hair and skin color, or keratin.  Africans, on the other hand, carry none or very little Neanderthal DNA.

http://dna-explained.com/2014/01/30/neanderthal-genome-further-defined-in-contemporary-eurasians/

A month later, a monumental paper was published that detailed the results of sequencing a 12,500 Clovis child, subsequently named Anzick or referred to as the Anzick Clovis child, in Montana.  That child is closely related to Native American people of today.

http://dna-explained.com/2014/02/13/clovis-people-are-native-americans-and-from-asia-not-europe/

In June, another paper emerged where the authors had analyzed 8000 year old bones from the Fertile Crescent that shed light on the Neolithic area before the expansion from the Fertile Crescent into Europe.  These would be the farmers that assimilated with or replaced the hunter-gatherers already living in Europe.

http://dna-explained.com/2014/06/09/dna-analysis-of-8000-year-old-bones-allows-peek-into-the-neolithic/

Svante Paabo is the scientist who first sequenced the Neanderthal genome.  Here is a neanderthal mangreat interview and speech.  This man is so interesting.  If you have not read his book, “Neanderthal Man, In Search of Lost Genomes,” I strongly recommend it.

http://dna-explained.com/2014/07/22/finding-your-inner-neanderthal-with-evolutionary-geneticist-svante-paabo/

In the fall, yet another paper was released that contained extremely interesting information about the peopling and migration of humans across Europe and Asia.  This was just before Michael Hammer’s presentation at the Family Tree DNA conference, so I covered the paper along with Michael’s information about European ancestral populations in one article.  The take away messages from this are two-fold.  First, there was a previously undefined “ghost population” called Ancient North Eurasian (ANE) that is found in the northern portion of Asia that contributed to both Asian populations, including those that would become the Native Americans and European populations as well.  Secondarily, the people we thought were in Europe early may not have been, based on the ancient DNA remains we have to date.  Of course, that may change when more ancient DNA is fully sequenced which seems to be happening at an ever-increasing rate.

http://dna-explained.com/2014/10/21/peopling-of-europe-2014-identifying-the-ghost-population/

Lazaridis tree

Ancient DNA Available for Citizen Scientists

If I were to give a Citizen Scientist of the Year award, this year’s award would go unquestionably to Felix Chandrakumar for his work with the ancient genome files and making them accessible to the genetic genealogy world.  Felix obtained the full genome files from the scientists involved in full genome analysis of ancient remains, reduced the files to the SNPs utilized by the autosomal testing companies in the genetic genealogy community, and has made them available at GedMatch.

http://dna-explained.com/2014/09/22/utilizing-ancient-dna-at-gedmatch/

If this topic is of interest to you, I encourage you to visit his blog and read his many posts over the past several months.

https://plus.google.com/+FelixChandrakumar/posts

The availability of these ancient results set off a sea of comparisons.  Many people with Native heritage matched Anzick’s file at some level, and many who are heavily Native American, particularly from Central and South America where there is less admixture match Anzick at what would statistically be considered within a genealogical timeframe.  Clearly, this isn’t possible, but it does speak to how endogamous populations affect DNA, even across thousands of years.

http://dna-explained.com/2014/09/23/analyzing-the-native-american-clovis-anzick-ancient-results/

Because Anzick is matching so heavily with the Mexican, Central and South American populations, it gives us the opportunity to extract mitochondrial DNA haplogroups from the matches that either are or may be Native, if they have not been recorded before.

http://dna-explained.com/2014/09/23/analyzing-the-native-american-clovis-anzick-ancient-results/

Needless to say, the matches of these ancient kits with contemporary people has left many people questioning how to interpret the results.  The answer is that we don’t really know yet, but there is a lot of study as well as speculation occurring.  In the citizen science community, this is how forward progress is made…eventually.

http://dna-explained.com/2014/09/25/ancient-dna-matches-what-do-they-mean/

http://dna-explained.com/2014/09/30/ancient-dna-matching-a-cautionary-tale/

More ancient DNA samples for comparison:

http://dna-explained.com/2014/10/04/more-ancient-dna-samples-for-comparison/

A Siberian sample that also matches the Malta Child whose remains were analyzed in late 2013.

http://dna-explained.com/2014/11/12/kostenki14-a-new-ancient-siberian-dna-sample/

Felix has prepared a list of kits that he has processed, along with their GedMatch numbers and other relevant information, like gender, haplogroup(s), age and location of sample.

http://www.y-str.org/p/ancient-dna.html

Furthermore, in a collaborative effort with Family Tree DNA, Felix formed an Ancient DNA project and uploaded the ancient autosomal files.  This is the first time that consumers can match with Ancient kits within the vendor’s data bases.

https://www.familytreedna.com/public/Ancient_DNA

Recently, GedMatch added a composite Archaic DNA Match comparison tool where your kit number is compared against all of the ancient DNA kits available.  The output is a heat map showing which samples you match most closely.

gedmatch ancient heat map

Indeed, it has been a banner year for ancient DNA and making additional discoveries about DNA and our ancestors.  Thank you Felix.

Haplogroup Definition

That SNP tsunami that we discussed last year…well, it made landfall this year and it has been storming all year long…in a good way.  At least, ultimately, it will be a good thing.  If you asked the haplogroup administrators today about that, they would probably be too tired to answer – as they’ve been quite overwhelmed with results.

The Big Y testing has been fantastically successful.  This is not from a Family Tree DNA perspective, but from a genetic genealogy perspective.  Branches have been being added to and sawed off of the haplotree on a daily basis.  This forced the renaming of the haplogroups from the old traditional R1b1a2 to R-M269 in 2012.  While there was some whimpering then, it would be nothing like the outright wailing now that would be occurring as haplogroup named reached 20 or so digits.

Alice Fairhurst discussed the SNP tsunami at the DNA Conference in Houston in October and I’m sure that the pace hasn’t slowed any between now and then.  According to Alice, in early 2014, there were 4115 individual SNPs on the ISOGG Tree, and as of the conference, there were 14,238 SNPs, with the 2014 addition total at that time standing at 10,213.  That is over 1000 per month or about 35 per day, every day.

Yes, indeed, that is the definition of a tsunami.  Every one of those additions requires one of a number of volunteers, generally haplogroup project administrators to evaluate the various Big Y results, the SNPs and novel variants included, where they need to be inserted in the tree and if branches need to be rearranged.  In some cases, naming request for previously unknown SNPs also need to be submitted.  This is all done behind the scenes and it’s not trivial.

The project I’m closest to is the R1b L-21 project because my Estes males fall into that group.  We’ve tested several, and I’ll be writing an article as soon as the final test is back.

The tree has grown unbelievably in this past year just within the L21 group.  This project includes over 700 individuals who have taken the Big Y test and shared their results which has defined about 440 branches of the L21 tree.  Currently there are almost 800 kits available if you count the ones on order and the 20 or so from another vendor.

Here is the L21 tree in January of 2014

L21 Jan 2014 crop

Compare this with today’s tree, below.

L21 dec 2014

Michael Walsh, Richard Stevens, David Stedman need to be commended for their incredible work in the R-L21 project.  Other administrators are doing equivalent work in other haplogroup projects as well.  I big thank you to everyone.  We’d be lost without you!

One of the results of this onslaught of information is that there have been fewer and fewer academic papers about haplogroups in the past few years.  In essence, by the time a paper can make it through the peer review cycle and into publication, the data in the paper is often already outdated relative to the Y chromosome.  Recently a new paper was released about haplogroup C3*.  While the data is quite valid, the authors didn’t utilize the new SNP naming nomenclature.  Before writing about the topic, I had to translate into SNPese.  Fortunately, C3* has been relatively stable.

http://dna-explained.com/2014/12/23/haplogroup-c3-previously-believed-east-asian-haplogroup-is-proven-native-american/

10th Annual International Conference on Genetic Genealogy

The Family Tree DNA International Conference on Genetic Genealogy for project administrators is always wonderful, but this year was special because it was the 10th annual.  And yes, it was my 10th year attending as well.  In all these years, I had never had a photo with both Max and Bennett.  Everyone is always so busy at the conferences.  Getting any 3 people, especially those two, in the same place at the same time takes something just short of a miracle.

roberta, max and bennett

Ten years ago, it was the first genetic genealogy conference ever held, and was the only place to obtain genetic genealogy education outside of the rootsweb genealogy DNA list, which is still in existence today.  Family Tree DNA always has a nice blend of sessions.  I always particularly appreciate the scientific sessions because those topics generally aren’t covered elsewhere.

http://dna-explained.com/2014/10/11/tenth-annual-family-tree-dna-conference-opening-reception/

http://dna-explained.com/2014/10/12/tenth-annual-family-tree-dna-conference-day-2/

http://dna-explained.com/2014/10/13/tenth-annual-family-tree-dna-conference-day-3/

http://dna-explained.com/2014/10/15/tenth-annual-family-tree-dna-conference-wrapup/

Jennifer Zinck wrote great recaps of each session and the ISOGG meeting.

http://www.ancestorcentral.com/decennial-conference-on-genetic-genealogy/

http://www.ancestorcentral.com/decennial-conference-on-genetic-genealogy-isogg-meeting/

http://www.ancestorcentral.com/decennial-conference-on-genetic-genealogy-sunday/

I thank Family Tree DNA for sponsoring all 10 conferences and continuing the tradition.  It’s really an amazing feat when you consider that 15 years ago, this industry didn’t exist at all and wouldn’t exist today if not for Max and Bennett.

Education

Two educational venues offered classes for genetic genealogists and have made their presentations available either for free or very reasonably.  One of the problems with genetic genealogy is that the field is so fast moving that last year’s session, unless it’s the very basics, is probably out of date today.  That’s the good news and the bad news.

http://dna-explained.com/2014/11/12/genetic-genealogy-ireland-2014-presentations 

http://dna-explained.com/2014/09/26/educational-videos-from-international-genetic-genealogy-conference-now-available/

In addition, three books have been released in 2014.emily book

In January, Emily Aulicino released Genetic Genealogy, The Basics and Beyond.

richard hill book

In October, Richard Hill released “Guide to DNA Testing: How to Identify Ancestors, Confirm Relationships and Measure Ethnicity through DNA Testing.”

david dowell book

Most recently, David Dowell’s new book, NextGen Genealogy: The DNA Connection was released right after Thanksgiving.

 

Ancestor Reconstruction – Raising the Dead

This seems to be the year that genetic genealogists are beginning to reconstruct their ancestors (on paper, not in the flesh) based on the DNA that the ancestors passed on to various descendants.  Those segments are “gathered up” and reassembled in a virtual ancestor.

I utilized Kitty Cooper’s tool to do just that.

http://dna-explained.com/2014/10/03/ancestor-reconstruction/

henry bolton probablyI know it doesn’t look like much yet but this is what I’ve been able to gather of Henry Bolton, my great-great-great-grandfather.

Kitty did it herself too.

http://blog.kittycooper.com/2014/08/mapping-an-ancestral-couple-a-backwards-use-of-my-segment-mapper/

http://blog.kittycooper.com/2014/09/segment-mapper-tool-improvements-another-wold-dna-map/

Ancestry.com wrote a paper about the fact that they have figured out how to do this as well in a research environment.

http://corporate.ancestry.com/press/press-releases/2014/12/ancestrydna-reconstructs-partial-genome-of-person-living-200-years-ago/

http://www.thegeneticgenealogist.com/2014/12/16/ancestrydna-recreates-portions-genome-david-speegle-two-wives/

GedMatch has created a tool called, appropriately, Lazarus that does the same thing, gathers up the DNA of your ancestor from their descendants and reassembles it into a DNA kit.

Blaine Bettinger has been working with and writing about his experiences with Lazarus.

http://www.thegeneticgenealogist.com/2014/10/20/finally-gedmatch-announces-monetization-strategy-way-raise-dead/

http://www.thegeneticgenealogist.com/2014/12/09/recreating-grandmothers-genome-part-1/

http://www.thegeneticgenealogist.com/2014/12/14/recreating-grandmothers-genome-part-2/

Tools

Speaking of tools, we have some new tools that have been introduced this year as well.

Genome Mate is a desktop tool used to organize data collected by researching DNA comparsions and aids in identifying common ancestors.  I have not used this tool, but there are others who are quite satisfied.  It does require Microsoft Silverlight be installed on your desktop.

The Autosomal DNA Segment Analyzer is available through www.dnagedcom.com and is a tool that I have used and found very helpful.  It assists you by visually grouping your matches, by chromosome, and who you match in common with.

adsa cluster 1

Charting Companion from Progeny Software, another tool I use, allows you to colorize and print or create pdf files that includes X chromosome groupings.  This greatly facilitates seeing how the X is passed through your ancestors to you and your parents.

x fan

WikiTree is a free resource for genealogists to be able to sort through relationships involving pedigree charts.  In November, they announced Relationship Finder.

Probably the best example I can show of how WikiTree has utilized DNA is using the results of King Richard III.

wiki richard

By clicking on the DNA icon, you see the following:

wiki richard 2

And then Richard’s Y, mitochondrial and X chromosome paths.

wiki richard 3

Since Richard had no descendants, to see how descendants work, click on his mother, Cecily of York’s DNA descendants and you’re shown up to 10 generations.

wiki richard 4

While this isn’t terribly useful for Cecily of York who lived and died in the 1400s, it would be incredibly useful for finding mitochondrial descendants of my ancestor born in 1802 in Virginia.  I’d love to prove she is the daughter of a specific set of parents by comparing her DNA with that of a proven daughter of those parents!  Maybe I’ll see if I can find her parents at WikiTree.

Kitty Cooper’s blog talks about additional tools.  I have used Kitty’s Chromosome mapping tools as discussed in ancestor reconstruction.

Felix Chandrakumar has created a number of fun tools as well.  Take a look.  I have not used most of these tools, but there are several I’ll be playing with shortly.

Exits and Entrances

With very little fanfare, deCODEme discontinued their consumer testing and reminded people to download their date before year end.

http://dna-explained.com/2014/09/30/decodeme-consumer-tests-discontinued/

I find this unfortunate because at one time, deCODEme seemed like a company full of promise for genetic genealogy.  They failed to take the rope and run.

On a sad note, Lucas Martin who founded DNA Tribes unexpectedly passed away in the fall.  DNA Tribes has been a long-time player in the ethnicity field of genetic genealogy.  I have often wondered if Lucas Martin was a pseudonym, as very little information about Lucas was available, even from Lucas himself.  Neither did I find an obituary.  Regardless, it’s sad to see someone with whom the community has worked for years pass away.  The website says that they expect to resume offering services in January 2015. I would be cautious about ordering until the structure of the new company is understood.

http://www.dnatribes.com/

In the last month, a new offering has become available that may be trying to piggyback on the name and feel of DNA Tribes, but I’m very hesitant to provide a link until it can be determined if this is legitimate or bogus.  If it’s legitimate, I’ll be writing about it in the future.

However, the big news exit was Ancestry’s exit from the Y and mtDNA testing arena.  We suspected this would happen when they stopped selling kits, but we NEVER expected that they would destroy the existing data bases, especially since they maintain the Sorenson data base as part of their agreement when they obtained the Sorenson data.

http://dna-explained.com/2014/10/02/ancestry-destroys-irreplaceable-dna-database/

The community is still hopeful that Ancestry may reverse that decision.

Ancestry – The Chromosome Browser War and DNA Circles

There has been an ongoing battle between Ancestry and the more seasoned or “hard-core” genetic genealogists for some time – actually for a long time.

The current and most long-standing issue is the lack of a chromosome browser, or any similar tools, that will allow genealogists to actually compare and confirm that their DNA match is genuine.  Ancestry maintains that we don’t need it, wouldn’t know how to use it, and that they have privacy concerns.

Other than their sessions and presentations, they had remained very quiet about this and not addressed it to the community as a whole, simply saying that they were building something better, a better mousetrap.

In the fall, Ancestry invited a small group of bloggers and educators to visit with them in an all-day meeting, which came to be called DNA Day.

http://dna-explained.com/2014/10/08/dna-day-with-ancestry/

In retrospect, I think that Ancestry perceived that they were going to have a huge public relations issue on their hands when they introduced their new feature called DNA Circles and in the process, people would lose approximately 80% of their current matches.  I think they were hopeful that if they could educate, or convince us, of the utility of their new phasing techniques and resulting DNA Circles feature that it would ease the pain of people’s loss in matches.

I am grateful that they reached out to the community.  Some very useful dialogue did occur between all participants.  However, to date, nothing more has happened nor have we received any additional updates after the release of Circles.

Time will tell.

http://dna-explained.com/2014/11/18/in-anticipation-of-ancestrys-better-mousetrap/

http://dna-explained.com/2014/11/19/ancestrys-better-mousetrap-dna-circles/

DNA Circles 12-29-2014

DNA Circles, while interesting and somewhat useful, is certainly NOT a replacement for a chromosome browser, nor is it a better mousetrap.

http://dna-explained.com/2014/11/30/chromosome-browser-war/

In fact, the first thing you have to do when you find a DNA Circle that you have not verified utilizing raw data and/or chromosome browser tools from either 23andMe, Family Tree DNA or Gedmatch, is to talk your matches into transferring their DNA to Family Tree DNA or download to Gedmatch, or both.

http://dna-explained.com/2014/11/27/sarah-hickerson-c1752-lost-ancestor-found-52-ancestors-48/

I might add that the great irony of finding the Hickerson DNA Circle that led me to confirm that ancestry utilizing both Family Tree DNA and GedMatch is that today, when I checked at Ancestry, the Hickerson DNA Circle is no longer listed.  So, I guess I’ve been somehow pruned from the circle.  I wonder if that is the same as being voted off of the island.  So, word to the wise…check your circles often…they change and not always in the upwards direction.

The Seamy Side – Lies, Snake Oil Salesmen and Bullys

Unfortunately a seamy side, an underbelly that’s rather ugly has developed in and around the genetic genealogy industry.  I guess this was to be expected with the rapid acceptance and increasing popularity of DNA testing, but it’s still very unfortunate.

Some of this I expected, but I didn’t expect it to be so…well…blatant.

I don’t watch late night TV, but I’m sure there are now DNA diets and DNA dating and just about anything else that could be sold with the allure of DNA attached to the title.

I googled to see if this was true, and it is, although I’m not about to click on any of those links.

google dna dating

google dna diet

Unfortunately, within the ever-growing genetic genealogy community a rather large rift has developed over the past couple of years.  Obviously everyone can’t get along, but this goes beyond that.  When someone disagrees, a group actively “stalks” the person, trying to cost them their employment, saying hate filled and untrue things and even going so far as to create a Facebook page titled “Against<personname>.”  That page has now been removed, but the fact that a group in the community found it acceptable to create something like that, and their friends joined, is remarkable, to say the least.  That was accompanied by death threats.

Bullying behavior like this does not make others feel particularly safe in expressing their opinions either and is not conducive to free and open discussion. As one of the law enforcement officers said, relative to the events, “This is not about genealogy.  I don’t know what it is about, yet, probably money, but it’s not about genealogy.”

Another phenomenon is that DNA is now a hot topic and is obviously “selling.”  Just this week, this report was published, and it is, as best we can tell, entirely untrue.

http://worldnewsdailyreport.com/usa-archaeologists-discover-remains-of-first-british-settlers-in-north-america/

There were several tip offs, like the city (Lanford) and county (Laurens County) is not in the state where it is attributed (it’s in SC not NC), and the name of the institution is incorrect (Johns Hopkins, not John Hopkins).  Additionally, if you google the name of the magazine, you’ll see that they specialize in tabloid “faux reporting.”  It also reads a lot like the King Richard genuine press release.

http://urbanlegends.about.com/od/Fake-News/tp/A-Guide-to-Fake-News-Websites.01.htm

Earlier this year, there was a bogus institutional site created as well.

On one of the DNA forums that I frequent, people often post links to articles they find that are relevant to DNA.  There was an interesting article, which has now been removed, correlating DNA results with latitude and altitude.  I thought to myself, I’ve never heard of that…how interesting.   Here’s part of what the article said:

Researchers at Aberdeen College’s Havering Centre for Genetic Research have discovered an important connection between our DNA and where our ancestors used to live.

Tiny sequence variations in the human genome sometimes called Single Nucleotide Polymorphisms (SNPs) occur with varying frequency in our DNA.  These have been studied for decades to understand the major migrations of large human populations.  Now Aberdeen College’s Dr. Miko Laerton and a team of scientists have developed pioneering research that shows that these differences in our DNA also reveal a detailed map of where our own ancestors lived going back thousands of years.

Dr. Laerton explains:  “Certain DNA sequence variations have always been important signposts in our understanding of human evolution because their ages can be estimated.  We’ve known for years that they occur most frequently in certain regions [of DNA], and that some alleles are more common to certain geographic or ethnic groups, but we have never fully understood the underlying reasons.  What our team found is that the variations in an individual’s DNA correlate with the latitudes and altitudes where their ancestors were living at the time that those genetic variations occurred.  We’re still working towards a complete understanding, but the knowledge that sequence variations are connected to latitude and altitude is a huge breakthrough by itself because those are enough to pinpoint where our ancestors lived at critical moments in history.”

The story goes on, but at the bottom, the traditional link to the publication journal is found.

The full study by Dr. Laerton and her team was published in the September issue of the Journal of Genetic Science.

I thought to myself, that’s odd, I’ve never heard of any of these people or this journal, and then I clicked to find this.

Aberdeen College bogus site

About that time, Debbie Kennett, DNA watchdog of the UK, posted this:

April Fools Day appears to have arrived early! There is no such institution as Aberdeen College founded in 1394. The University of Aberdeen in Scotland was founded in 1495 and is divided into three colleges: http://www.abdn.ac.uk/about/colleges-schools-institutes/colleges-53.php

The picture on the masthead of the “Aberdeen College” website looks very much like a photo of Aberdeen University. This fake news item seems to be the only live page on the Aberdeen College website. If you click on any other links, including the link to the so-called “Journal of Genetic Science”, you get a message that the website is experienced “unusually high traffic”. There appears to be no such journal anyway.

We also realized that Dr. Laerton, reversed, is “not real.”

I still have no idea why someone would invest the time and effort into the fake website emulating the University of Aberdeen, but I’m absolutely positive that their motives were not beneficial to any of us.

What is the take-away of all of this?  Be aware, very aware, skeptical and vigilant.  Stick with the mainstream vendors unless you realize you’re experimenting.

King Richard

King Richard III

The much anticipated and long-awaited DNA results on the remains of King Richard III became available with a very unexpected twist.  While the science team feels that they have positively identified the remains as those of Richard, the Y DNA of Richard and another group of men supposed to have been descended from a common ancestor with Richard carry DNA that does not match.

http://dna-explained.com/2014/12/09/henry-iii-king-of-england-fox-in-the-henhouse-52-ancestors-49/

http://dna-explained.com/2014/12/05/mitochondrial-dna-mutation-rates-and-common-ancestors/

Debbie Kennett wrote a great summary article.

http://cruwys.blogspot.com/2014/12/richard-iii-and-use-of-dna-as-evidence.html

More Alike than Different

One of the life lessons that genetic genealogy has held for me is that we are more closely related that we ever knew, to more people than we ever expected, and we are far more alike than different.  A recent paper recently published by 23andMe scientists documents that people’s ethnicity reflect the historic events that took place in the part of the country where their ancestors lived, such as slavery, the Trail of Tears and immigration from various worldwide locations.

23andMe European African map

From the 23andMe blog:

The study leverages samples of unprecedented size and precise estimates of ancestry to reveal the rate of ancestry mixing among American populations, and where it has occurred geographically:

  • All three groups – African Americans, European Americans and Latinos – have ancestry from Africa, Europe and the Americas.
  • Approximately 3.5 percent of European Americans have 1 percent or more African ancestry. Many of these European Americans who describe themselves as “white” may be unaware of their African ancestry since the African ancestor may be 5-10 generations in the past.
  • European Americans with African ancestry are found at much higher frequencies in southern states than in other parts of the US.

The ancestry proportions point to the different regional impacts of slavery, immigration, migration and colonization within the United States:

  • The highest levels of African ancestry among self-reported African Americans are found in southern states, especially South Carolina and Georgia.
  • One in every 20 African Americans carries Native American ancestry.
  • More than 14 percent of African Americans from Oklahoma carry at least 2 percent Native American ancestry, likely reflecting the Trail of Tears migration following the Indian Removal Act of 1830.
  • Among self-reported Latinos in the US, those from states in the southwest, especially from states bordering Mexico, have the highest levels of Native American ancestry.

http://news.sciencemag.org/biology/2014/12/genetic-study-reveals-surprising-ancestry-many-americans?utm_campaign=email-news-weekly&utm_source=eloqua

23andMe provides a very nice summary of the graphics in the article at this link:

http://blog.23andme.com/wp-content/uploads/2014/10/Bryc_ASHG2014_textboxes.pdf

The academic article can be found here:

http://www.cell.com/ajhg/home

2015

So what does 2015 hold? I don’t know, but I can’t wait to find out. Hopefully, it holds more ancestors, whether discovered through plain old paper research, cousin DNA testing or virtually raised from the dead!

What would my wish list look like?

  • More ancient genomes sequenced, including ones from North and South America.
  • Ancestor reconstruction on a large scale.
  • The haplotree becoming fleshed out and stable.
  • Big Y sequencing combined with STR panels for enhanced genealogical research.
  • Improved ethnicity reporting.
  • Mitochondrial DNA search by ancestor for descendants who have tested.
  • More tools, always more tools….
  • More time to use the tools!

Here’s wishing you an ancestor filled 2015!